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The PI3 virus infects the upper respiratory mucosa, where it is shed in aerosols and by direct contact. The role of PI3 in BRD is to predispose cattle to concurrent infections with IBR virus or bacterial respiratory pathogens.
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Clinical effects include the classic respiratory signs of cough, fever, serous nasal and ocular discharge, increased respiratory rate and dyspenea (difficult breathing).
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Diagnosis may be made on clinical signs typical of viral respiratory disease, including fever, depression, inappetance, nasal discharge, spontaneous coughing, and increased respiratory rate.
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There is no specific anti-PI3 therapy. Treatment is limited to antibacterial therapy for secondary bacterial infections and supportive treatment.
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Vaccination with TSV-2®, INFORCE™ 3, Bovi-Shield GOLD® 4, Bovi-Shield GOLD® 5, Bovi-Shield GOLD FP® 5 L5 HB, Bovi-Shield GOLD FP® 5 VL5 HB, Bovi-Shield GOLD FP® 5, Bovi-Shield GOLD FP® 5 L5, Bovi-Shield GOLD FP® 5 VL5, CattleMaster® 4+VL5, CattleMaster® GOLD FP® 5, CattleMaster® GOLD FP® 5 L5, PregGuard GOLD FP® 10 may help prevent, control, or lessen the severity of the disease.