Print page content Print
Increase text size Decrease text size
Text Size
UNDERSTANDING CANINE ALLERGIC DISEASE
CANINE ALLERGIC DISEASE

The Itch Cycle

The Itch Cycle

New understanding of the pathobiology of canine pruritus is helping to improve treatments

Welcome to itchcycle.com, a resource for learning about the cycle of itch and its role in canine pruritus.

The itch cycle begins when allergens cross the skin barrier, triggering T-cell activation and sensitization of immune cells. When re-exposed to the allergen, these cells release pruritogenic and pro-inflammatory cytokines, causing scratching and starting the cycle again.

Evolving understanding of the biochemical pathways of the itch cycle may lead to precisely targeted treatments designed to interrupt the cycle and halt itch. To learn more, review the videos below.

Resources



Pathobiology of Canine Allergic Disease Full-Length Video (ENGLISH) (.wmv - 44.9 MB)

Pathobiology of Canine Allergic Disease Full-Length Video (ENGLISH) (.mp4 - 44.3 MB)

Pathobiology of Canine Allergic Disease Video (NEDERLANDSE) (.mp4 - 49.1 MB)

Pathobiology of Canine Allergic Disease Video (FRANÇAIS) (.mp4 - 49.5 MB)

Pathobiology of Canine Allergic Disease Video (DEUTSCH) (.mp4 - 49.3 MB)

Pathobiology of Canine Allergic Disease Video (ITALIANO) (.mp4 - 49.5 MB)

Pathobiology of Canine Allergic Disease Video (日本語) (.mp4 - 49.5 MB)

Pathobiology of Canine Allergic Disease Video (ESPAÑOL) (.mp4 - 49.5 MB)

All trademarks are the property of Zoetis Inc., its affiliates and/or its licensors.
CAD-00145 ©2016 Zoetis Inc. All rights reserved. March 2016.

CONTACT US

1-888-963-8471

We are Mon–Fri, 8:30am–8:00pm ET

This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2020 Zoetis Services LLC. All rights reserved.