CERENIA®
FAQs
FAQ
WHAT IS CERENIA?

CERENIA is an anti-emetic (anti-vomiting) product indicated for the treatment and prevention of acute emesis (including emesis induced by chemotherapy) and the prevention of vomiting due to motion sickness in dogs. CERENIA is also indicated for the treatment of acute vomiting in cats.

Prescribing Information

HOW DOES CERENIA WORK?

CERENIA is an NK-1 receptor antagonist, and acts to prevent Substance P (a neurotransmitter) from binding to NK-1 receptors. NK-1 receptors have been recently identified as a key receptor involved in the vomiting reflex and these receptors are found in high concentrations within the chemoreceptor trigger zone (CRTZ) and within the emetic center, where all emetic stimuli ultimately converge. By blocking the binding of Substance P to NK-1 receptors within the emetic center, CERENIA is effective against vomiting stimuli regardless of the origin.

WHEN TREATING A DOG FOR MOTION SICKNESS, WHAT IS THE RECOMMENDATION WITH RESPECT TO FEEDING, TABLET ADMINISTRATION AND CAR TRAVEL?

According to the product label, dogs should be dosed 2 hours prior to travel and following a 1 hour fast. Zoetis recommends that the tablets are administered with a small amount of food to reduce post-dosing emesis and does not recommend a prolonged fast prior to dosing.

WHAT ARE THE INDICATIONS FOR CERENIA?

CERENIA INJECTABLE indications:
CERENIA INJECTABLE Solution is indicated for the prevention and treatment of acute vomiting in dogs ≥8 weeks and for the treatment of vomiting in cats ≥16 weeks.

CERENIA TABLETS indications:
CERENIA TABLETS are indicated for the prevention of acute vomiting in dogs 8 weeks and older.

CERENIA TABLETS are indicated for the prevention of vomiting due to motion sickness in dogs 16 weeks and older.

IMPORTANT SAFETY INFORMATION: CERENIA Injectable is recommended for vomiting in cats 16 weeks and older, and acute vomiting in dogs 8 weeks and older. CERENIA Tablets are recommended for acute vomiting in dogs 8 weeks and older, and for prevention of vomiting due to motion sickness in dogs 16 weeks and older. Safe use of CERENIA has not been evaluated in breeding, pregnant, or nursing cats and dogs, those with gastrointestinal obstruction, or those that have ingested toxins. Use with caution in cats and dogs with hepatic dysfunction. Pain/vocalization upon injection is a common side effect. In people, topical exposure may elicit localized allergic skin reactions, and repeated or prolonged exposure may lead to skin sensitization. For more information, read the full prescribing information.