Expand your approach to reduce the risks of BVD

Biosecurity and testing are essential components alongside immunization

Bovine viral diarrhea virus (BVDV) continues to be a vexing problem for cow/calf producers. BVDV is spread in multiple ways and the risk control effort needs to have a multi-pronged approach. 

According to Dr. Paul Walz, professor of pathology at Auburn University, there are three steps to controlling BVDV infections:

  • Biosecurity
  • Immunization
  • Testing

Vaccinating is the act of giving the animal a vaccine, explained Dr. Walz, while immunization is when the animal has an immune response to the vaccine. He said ideally producers will give two doses of modified-live virus reproductive vaccine in replacement heifers before they are bred for the first time, with the last dose given approximately 30 days prior to breeding. 

Annual revaccination with a modified-live virus vaccine, like Bovi-Shield Gold FP® 5 VL5, gives effective protection against BVDV infections. If a modified-live virus program in the mature cowherd doesn’t work for the operation, a killed BVDV reproductive vaccine, like CattleMaster Gold FP® 5, at pregnancy check time can also provide protection for the herd against BVDV infection.

Once producers have established a strong vaccination protocol for the cow herd, it is time to look beyond immunization to apply additional tools and management to reduce BVDV risks. 

A cow persistently infected (PI) with BVDV will always have a calf that is persistently infected with BVDV. Dr. Walz points out the PI calf is a central figure in how BVDV maintains itself within a herd and how BVDV travels from herd to herd. But the risk for spreading BVDV extends throughout an operation, to equipment, visitors to the farm and fence-line contact among animals. 

With so many avenues of BVDV transmission, the work to control the risk begins with biosecurity. 

“We cannot rely on immunization to 100% prevent PI infections, nor can we look at our diagnostic test to pick up every single PI animal, so biosecurity is a really good way to reduce risk,” Dr. Walz said. 

The main path for BVDV introduction to a herd is through new cattle. The “Trojan dam” — a highly immune cow that is a PI carrier in its reproductive tract and uterus — makes detection difficult, explained Dr. Walz. The cow would pass any test for BVDV, but it is, nonetheless, an infected animal. Producers who purchase pregnant animals, or are bringing them back from a heifer raiser, must contain them for biosecurity purposes to reduce BVDV spread. 

“If at all possible, test for PI status of the newborn calves on the new cows rather than allowing those cows to calve within the general population of cows,” Dr. Walz said.

Dr. Walz shared some other essential components of effective biosecurity measures:

  • Avoid bringing in new animals unless they’ve been tested.
  • Isolate sick animals from healthy ones.
  • Move dead animals away from the barn.
  • Pay special attention to young animals.
  • Practice general hygiene — soap, water and general disinfection.
  • Monitor visitors and be aware of how they can transmit BVDV from farm to farm.

The importance of taking the time to test
“We have excellent tests available for BVDV,” Dr. Walz said. “We have better tests for BVDV than we have for a lot of our other diseases, including infectious bovine rhinotracheitis.”

Dr. Walz said testing the newborn calf is essentially testing the dam, and knowing those results can set in motion biosecurity measures and other steps. There are numerous ways to test, and working with a diagnostic laboratory can help produce the most useful results. 

“Your diagnostic lab is a tremendous resource for testing, but also a tremendous resource for information on how to test and when to test,” Dr. Walz said.

For more information on biosecurity and taking steps to reduce the risk of BVDV, work with your local veterinarian, or visit FetalCalfProtection.com to learn about vaccine options from Zoetis to help protect the cow and unborn calf. 

About Zoetis 
Zoetis is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 65 years of experience in animal health, Zoetis discovers, develops, manufactures and commercializes medicines, vaccines and diagnostic products, which are complemented by biodevices, genetic tests and a range of services. Zoetis serves veterinarians, livestock producers and people who raise and care for farm and companion animals with sales of its products in more than 100 countries. In 2018, the company generated annual revenue of $5.8 billion with approximately 10,000 employees. For more information, visit https://www.zoetisus.com.

For more information, contact:
Kathleen McGinty

Lori Maude
Bader Rutter



Mon–Fri, 8:30am–8:00pm ET

This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2022 Zoetis Services LLC. All rights reserved.