Getting more than a good deal

Commingled cattle can bring home increased risk of bovine respiratory disease (BRD)

At a sale barn, everyone is looking for a good deal. There’s opportunity for profit, but commingling cattle from different backgrounds isn’t always a bargain. The bacteria cattle can be exposed to put them at risk for developing bovine respiratory disease (BRD).1

Charlie Durbin, DVM, St. Peter, Ill., notes that the stress of the typical sale barn situation, combined with potential exposure to other sick cattle, can easily lead to BRD — leaving producers with increased time spent caring for sick cattle, reduced average daily gains or even increased death loss.1

To help protect producer’s profits, Dr. Durbin suggests good management and a solid treatment plan that starts as soon as cattle step off the truck. One of his key recommendations is using an antimicrobial that can be administered to incoming cattle and will continue working for at least a week without retreating. This helps reduce management time pulling and re-treating sick cattle, and helps reduce handling stress on the animal.

“You need several days of antimicrobial working for you so you don’t have to go back and run them through the chute again and stress them out that much more,” Dr. Durbin notes.

With nearly three decades experience battling BRD, Dr. Durbin says a long-lasting antimicrobial helps keep cattle healthy, and it leaves time for producers to invest in other aspects of the operation.

Dr. Durbin recommends EXCEDE® (ceftiofur crystalline free acid) Sterile Suspension for treatment and control of BRD, especially in risky sale barn situations. EXCEDE provides one week (seven days) of therapy in just one dose — helping to reduce both stress on cattle and time spent managing sick cattle.

Not properly managing the effects of BRD can reduce an animal’s performance throughout its entire life.1 When producers know what situations — like commingling cattle — can result in BRD, they have a head start in managing the disease and protecting against lost performance and profits.

“When they come in with droopy ears, watering eyes, snot hanging out of their nose, are gaunt — one shot of EXCEDE will do the trick,” Dr. Durbin says.

Important Safety Information: As with all drugs, the use of EXCEDE is contraindicated in animals with known allergy to ceftiofur or to the ß-lactam group (penicillins and cephalosporins) of antimicrobials. Though safe in cattle when properly administered, inadvertent intra-arterial injection is possible and fatal. EXCEDE has a pre-slaughter withdrawal time of 13 days in cattle. Do not use in calves to be processed for veal.

Prescribing Information

For more information, contact:
Michelle Tollefson
Pfizer Animal Health

Kori Conley
Bader Rutter

1Irsik M. Bovine respiratory disease associated with Mannheimia haemolytica or Pasteurella multocida. University of Florida IFAS Extension. Available at: Accessed Feb. 17, 2011.



Mon–Fri, 8:30am–6:30pm ET

This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2022 Zoetis Services LLC. All rights reserved.