Once-daily treatment for canine atopic dermatitis
Delivers 6-in-1 parasite protection for cats
Valuable discounts, expert information, and tips
See how injectable medications offer value beyond the prescription
The first and only FDA-Approved veterinary antiemetic
The first long-lasting monoclonal antibody therapy for canine atopic dermatitis
Vaccination for the prevention of respiratory disease caused by BRSV
The beef industry’s No. 1 branded preconditioning program
Exclusive pricing program for Cattle producers
Outstanding protection against costly respiratory and reproductive diseases
Treatment and control of gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites
Innovative food safety products that help deliver a farm-to-fork solution for beef
The most comprehensive guarantee available
First and only FDA-approved antibiotic for horses that offers a full course of therapy in just two doses
Annual vaccination with CORE EQ INNOVATOR helps provide the protection your horse needs
Treats and controls encysted small strongyles, bots and roundworms. QUEST PLUS contains an additional active ingredient for efficacy against tapeworms
Patented and scientific method of determining fair service pricing to improve your clinic's profitability
Connect directly to valuable dairy management resources and experts
The most "veterinarian recommended" and "producer used" prostaglandin in the market
Delivers the peace of mind and profitability that come with no milk discard
Effective and convenient treatment for acute metritis in cattle
Working together to improve reproduction
One injection treats and controls swine respiratory disease for 7 days
Protect sows and gilts from costly breeding herd diseases — parvovirus, leptospirosis and erysipelas
The industry standard for in ovo technology.
Full automation solutions for hatchery automation
Prevention and control of necrotic enteritis, increased rate of weight gain and improved feed efficiency in poultry
for the prevention of coccidiosis in poultry
modified-live vaccine that helps poultry companies reduce their overall Salmonella load
Blood glucose monitoring system
Smart new diagnostics platform that can reinvent your in-house diagnostic routines
Detect Johne’s Disease with confidence in cattle and goat herds
Simple and effective detection of a deadly Feline Virus
Accurate, affordable and easy to use
Order Beef Genetics products online
Order Dairy Genetics products online
Delivers reliable predictions of genetic merit based on test results of core traits
Represents the latest advancement in Angus genotyping technology.
Register today to learn more
Become a more effective leader
Looking for a tailored experience?
Earn continuing education credits and stay current on industry developments with Zoetis’ convenient, on-demand learning solutions.
Veterinarians, Veterinarian Techs, Business Owners, and Farm Hands
Launch your veterinary career
Veterinarian Students and Recent Graduates
Animal health expertise and results-focused resources for high-performing teams and leaders.
Veterinarians, Dairy producers, Beef producers, Equine Specialists, Pork producers, Poultry producers, Managers, Business Owners and Staff
Home / NEWS & MEDIA / Head-to-head Farm Trials Prove Effectiveness of FACTREL® Injection
Producers can confidently rely on this reproduction tool to improve breeding efficiency
FLORHAM PARK, N.J., Oct. 20, 2015 — Three on-farm studies of more than 12,000 cows showed FACTREL® Injection (gonadorelin injection), when used with LUTALYSE® Injection (dinoprost injection), effectively helped synchronize estrous cycles and achieve equivalent conception risks as compared with other on-farm fixed-time artificial insemination (AI) protocols in lactating dairy cows.
One of those studies, the dairy industry’s largest fixed-time AI non-inferiority study to date involving 5,827 cows, showed FACTREL was not statistically different when used in fixed-time AI protocols as compared to competitive GnRH products containing gonadorelin diacetate tetrahydrate. The first-service conception risk in cows treated with FACTREL was noninferior to farm protocols using competitive GnRH products. In addition, there was no significant difference (P=0.65) in first-service conception risk between those treated with a 2-mL dose of FACTREL (37.6%) and those treated with farm protocols using competitive products (39%).1
In a second and independent study of 3,938 cows, the conception risk of animals treated with a 2-mL dose of FACTREL was not statistically different (P>0.10) to those treated with Cystorelin® (gonadorelin diacetate tetrahydrate) in a fixed-time AI program.2
A third and independent study of 2,620 cows from 40 Canadian herds, found no difference (P=0.84) in first-time conception risk between its two study groups. Furthermore, FACTREL was found to be noninferior to Fertiline® (gonadorelin acetate) in a fixed-time AI protocol.3
“Using FACTREL and LUTALYSE in combination provides an effective, U.S. Food and Drug Administration (FDA)-approved method of synchronizing estrus using a variety of fixed-time AI programs,” said Ken Learmont, DVM, senior veterinarian, Dairy Technical Services, Zoetis. “With more than 12,000 combined cows studied, producers can have the peace of mind that FACTREL is a safe and efficacious product when used according to its label.”
FACTREL now offered in a larger, more convenient vial sizeZoetis continues to focus on convenience for producers by now offering FACTREL in a 50-mL vial size. The larger bottle size delivers ease by allowing producers to treat up to 25 cows per bottle, which is more than most other GnRH products on the market.
For the convenience of producers, Zoetis is now offering FACTREL® Injection (gonadorelin injection) in a 50-mL vial size.
With approved use of Zoetis products for fixed-time AI, customers can use LUTALYSE and FACTREL in many of the synchronization protocols recommended by the Dairy Cattle Reproduction Council. The FDA approval of FACTREL and LUTALYSE includes a flexible schedule and the only flexible dose of a GnRH product, allowing producers to develop protocols that fit their dairy’s needs.
Ken Mitchell, DVM, of Valley Veterinarians based in Tulare, California, expressed confidence in FACTREL: “We were involved in a trial to test the efficacy of FACTREL used in a simple timed AI sequence. At the end of the trial, as a whole, our reproductive program on this dairy became noticeably more efficient during that period of time.”
Committed to reproductive success Raising the bar in dairy reproduction requires a team effort. Zoetis understands the changing needs of today’s dairy industry and is committed to providing flexible, comprehensive on-label solutions that are consistent with management practices.
“This new offering is a continuation of Zoetis’ commitment to providing the industry with comprehensive reproductive management solutions,” Dr. Learmont said. “We’ll continue to invest in new, practical and on-label solutions and research that will help improve reproduction so veterinarians and producers can use them with confidence. This provides producers the peace of mind they are doing the right thing for their dairy.”
For more than 30 years, as the leader in dairy reproduction research, support and technical services, Zoetis has been delivering innovations to help producers and veterinarians improve reproductive programs.
To learn more about FACTREL and LUTALYSE as an on-label synchronization program, visit DairyReproSolutions.com or contact your veterinarian or Zoetis representative.
IMPORTANT SAFETY INFORMATION FOR FACTREL: FACTREL Injection is for use in cattle only. Please see full Prescribing Information.
IMPORTANT SAFETY INFORMATION FOR LUTALYSE: Women of childbearing age and persons with respiratory problems should exercise extreme caution when handling LUTALYSE. LUTALYSE is readily absorbed through the skin and may cause abortion and/or bronchiospasms, therefore spillage on the skin should be washed off immediately with soap and water. Aseptic technique should be used to reduce the possibility of post-injection clostridial infections. Do not administer LUTALYSE in pregnant cattle unless cessation of pregnancy is desired. See full Prescribing Information.
About Zoetis Zoetis (zō-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 60 years of experience in animal health, Zoetis discovers, develops, manufactures and markets veterinary vaccines and medicines, complemented by diagnostic products and genetic tests and supported by a range of services. In 2014, the company generated annual revenue of $4.8 billion. With approximately 10,000 employees worldwide at the beginning of 2015, Zoetis serves veterinarians, livestock producers and people who raise and care for farm and companion animals with sales of its products in 120 countries. For more information, visit www.zoetisUS.com.
For Further Information,Contact :
Kristina HopkinsBader Rutter262email@example.com
1 Data on File, Study Report No. 13PETREPRO01-08D, Zoetis Inc. 2 Poock S, Lucy M. Conception rate for postpartum dairy cows treated with different gonadorelin (GnRH) products for first or resynchronized timed AI. Presented at 2015 Midwest ADSA/ASAS Meeting, Des Moines, IA, March 16-18, 2015.3 Caldwell V, Tison N, Martineau R, Dubuc J, Des Côteaux L. Non-inferiority randomized field clinical trial of two GnRH commercial products used in a systematic double-ovsynch protocol at first breeding in dairy cows, in Proceedings. Am Assoc Bov Pract Conf 2014.
All trademarks are the property of Zoetis Inc., its affiliates and/or its licensors. All other trademarks are the property of their respective owners.
Mon–Fri, 8am–8pm ET
You are leaving the country website to access another site in the group.
Regulatory constraints and medical practices vary from country to country. Consequently, the information provided on the site in which you enter may not be suitable for use in your country.
This site is intended for U.S. Animal Healthcare Professionals.
All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2017 Zoetis Services LLC. All rights reserved.