Once-daily treatment for canine atopic dermatitis
Delivers 6-in-1 parasite protection for cats
Valuable discounts, expert information, and tips
See how injectable medications offer value beyond the prescription
The first and only FDA-Approved veterinary antiemetic
The first long-lasting monoclonal antibody therapy for canine atopic dermatitis
Vaccination for the prevention of respiratory disease caused by BRSV
The beef industry’s No. 1 branded preconditioning program
Exclusive pricing program for Cattle producers
Outstanding protection against costly respiratory and reproductive diseases
Treatment and control of gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites
Innovative food safety products that help deliver a farm-to-fork solution for beef
The most comprehensive guarantee available
First and only FDA-approved antibiotic for horses that offers a full course of therapy in just two doses
Annual vaccination with CORE EQ INNOVATOR helps provide the protection your horse needs
Treats and controls encysted small strongyles, bots and roundworms. QUEST PLUS contains an additional active ingredient for efficacy against tapeworms
Patented and scientific method of determining fair service pricing to improve your clinic's profitability
Connect directly to valuable dairy management resources and experts
The most "veterinarian recommended" and "producer used" prostaglandin in the market
Delivers the peace of mind and profitability that come with no milk discard
Effective and convenient treatment for acute metritis in cattle
Working together to improve reproduction
One injection treats and controls swine respiratory disease for 7 days
Protect sows and gilts from costly breeding herd diseases — parvovirus, leptospirosis and erysipelas
The industry standard for in ovo technology.
Full automation solutions for hatchery automation
Prevention and control of necrotic enteritis, increased rate of weight gain and improved feed efficiency in poultry
for the prevention of coccidiosis in poultry
modified-live vaccine that helps poultry companies reduce their overall Salmonella load
Blood glucose monitoring system
Smart new diagnostics platform that can reinvent your in-house diagnostic routines
Detect Johne’s Disease with confidence in cattle and goat herds
Simple and effective detection of a deadly Feline Virus
Accurate, affordable and easy to use
Order Beef Genetics products online
Order Dairy Genetics products online
Delivers reliable predictions of genetic merit based on test results of core traits
Represents the latest advancement in Angus genotyping technology.
Register today to learn more
Become a more effective leader
Looking for a tailored experience?
Earn continuing education credits and stay current on industry developments with Zoetis’ convenient, on-demand learning solutions.
Veterinarians, Veterinarian Techs, Business Owners, and Farm Hands
Launch your veterinary career
Veterinarian Students and Recent Graduates
Animal health expertise and results-focused resources for high-performing teams and leaders.
Veterinarians, Dairy producers, Beef producers, Equine Specialists, Pork producers, Poultry producers, Managers, Business Owners and Staff
Home / NEWS & MEDIA / Horses Vaccinated with WEST NILE-INNOVATOR® and FLUVAC INNOVATOR® Generated Four Times the Immune Response to West Nile Virus
According to research, big one-shot combination vaccines may deliver a lower immune response than expected. While equine vaccine combinations that include West Nile virus and equine influenza/equine herpesvirus (rhino) antigens in a single formulation may be convenient, the horse’s immunity could be sacrificed. A study showed that separate administration of WEST NILE-INNOVATOR® and FLUVAC INNOVATOR® generated four times the immune response to West Nile virus than was produced by a big one-shot combination vaccine.1
The study compared serological responses to West Nile virus in 280 horses following six difference vaccine regimens. Vaccination regimens that combined West Nile virus with Eastern and Western equine encephalomyelitis (EEE/WEE) viruses and tetanus antigens in a single formulation appeared to impact the West Nile virus antibody response compared to vaccination regimens that employed concurrent administration of the West Nile virus component and the EEE virus, WEE virus and tetanus antigens.1
“Dividing antigens into concurrent, separate injections may help increase the horse’s immune response to West Nile.” said Kevin Hankins, DVM, senior veterinarian, Equine Technical Services, Zoetis. “While big one-shot combination vaccines may offer convenience, when developing vaccine programs for West Nile virus protection, veterinarians and horse owners should consider the implications of lower West Nile virus antibody responses in horses vaccinated with a West Nile virus combination vaccine. Though combination vaccines may provide some convenience, optimization of West Nile virus immune response could likely pose a substantial criterion for vaccine selection.” As every horse has a unique set of needs, a standard one-size-fits-all equine vaccination program does not exist. The American Association of Equine Practitioners (AAEP) Vaccination Guidelines recommend an evaluation of each individual horse’s situation and vaccinating according to his needs.2 Dividing West Nile and equine influenza/equine herpesvirus (rhino) vaccinations into separate injections allows tailoring of each horse’s vaccination program.
The Equine Immunization Support Guarantee from Zoetis, the most comprehensive guarantee available, delivers additional confidence in your equine vaccination program. With the Equine Immunization Support Guarantee, if a horse shows clinical signs for an equine disease for which he was vaccinated, Zoetis will help cover the diagnostic investigation to determine with what the horse is infected. If diagnostics confirm disease, Zoetis will also cover diagnostic and therapeutic charges up to $5,000. To be eligible, a horse must be vaccinated by a veterinarian. Diseases covered by the Equine Immunization Support Guarantee include: rhinopneumonitis (equine herpesvirus types 1 and 4, respiratory), West Nile, equine influenza, tetanus, Eastern equine encephalitis (EEE), Western equine encephalitis (WEE) and Venezuelan equine encephalitis (VEE).
WEST NILE-INNOVATOR and FLUVAC INNOVATOR are the veterinarian and horse owner’s first choice for equine disease protection.3 Only INNOVATOR vaccines are adjuvanted with MetaStim®, a proprietary adjuvant system designed for safe, enhanced presentation of antigens to the horse’s immune system, featuring a dual-phase formulation shown to stimulate both cell-mediated and humoral immunity to West Nile virus for improved immune responses.4,5
To learn more about how administering core and risk antigens separately helps protect horses from disease, visit www.FourTimesMore.com.
About Zoetis Zoetis (zō-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 60 years of experience in animal health, Zoetis discovers, develops, manufactures and markets veterinary vaccines and medicines, complemented by diagnostic products and genetic tests and supported by a range of services. Zoetis serves veterinarians, livestock producers and people who raise and care for farm and companion animals with sales of its products in more than 100 countries. In 2015, the company generated annual revenue of $4.8 billion with approximately 9,000 employees. For more information, visit www.zoetisUS.com.
For more information, contact: Sally AmtmannZoetis firstname.lastname@example.org
Kassi HoxmeierBader Rutter262email@example.com
References:1 Cortese V, Hankins K, Holland R, Syvrud K. Serologic Responses of West Nile Virus Seronegative Mature Horses to West Nile Virus Vaccines. J Equine Vet Sci. 2013;33:1101-1105.2 American Association of Equine Practitioners. Vaccination Guidelines. 2012. http://www.aaep.org/info/vaccination-guidelines. Accessed June 1, 2016. 3 Data on file, MDI sales data for WEST NILE-INNOVATOR and FLUVAC INNOVATOR as of 12/31/15, Zoetis LLC.4 Davis EG, Zhang Y, Tuttle J, et al. Investigation of antigen specific lymphocyte responses in healthy horses vaccinated with an inactivated West Nile virus vaccine. Vet Immunol Immunopathol. 2008;126(3-4):293-301.5 Davis EG, Bello NM, Bryan AJ, et al. Characterisation of immune responses in healthy foals when a multivalent vaccine protocol was initiated at age 90 or 180 days. Equine Vet J. 2014. doi:10.1111/evj.12350.
Mon–Fri, 8am–8pm ET
You are leaving the country website to access another site in the group.
Regulatory constraints and medical practices vary from country to country. Consequently, the information provided on the site in which you enter may not be suitable for use in your country.
This site is intended for U.S. Animal Healthcare Professionals.
All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2017 Zoetis Services LLC. All rights reserved.