Lepto Hardjo-Bovis Could Be Lurking

Help avoid this quiet threat with a complete reproductive vaccine program

What’s hiding in your herd? On many beef operations, Lepto hardjo-bovis (LHB) — a primary cause of bovine leptospirosis in U.S. cow herds and a leading contributor to reproductive loss — could be quietly harming cattle and costing producers.1

Cattle infected with LHB typically appear clinically normal but can shed the bacteria for months or years, putting the entire herd at risk for poor reproductive performance, early embryonic death, delayed breeding, abortions, weak or stillborn calves and unexplained infertility.2,3, Early abortions may precede pregnancy checking and be wrongly identified, leaving producers unaware of an underlying disease problem.

“There are often no obvious clinical signs for LHB infection — only decreased fertility and early embryonic death. This is what makes it so difficult to detect,” says Rich Linhart, DVM, DACT, Cattle and Equine Technical Services, Pfizer Animal Health.

The only way to help ensure a herd, and the producer’s bottom line, is protected against LHB is to utilize a complete reproductive vaccine that provides protection where it matters most — the reproductive tract. For this, producers can look to the only viral combination vaccine, BOVI-SHIELD GOLD FP® 5 VL5 HB,* which helps:

  • Prevent establishment of LHB in the reproductive tract.
  • Provide 365 days of superior protection against Lepto hardjo-bovis infections in the kidneys and shedding in the urine.
  • Prevent abortions caused by infectious bovine rhinotracheitis (IBR) virus and bovine viral diarrhea (BVD) Types 1 and 2 persistent infections (PI) for at least 365 days.
  • Prevent Campylobacter fetus (vibriosis), parainfluenza type 3 (PI3) virus and bovine respiratory syncytial virus (BRSV).

No other vaccines carry the “prevention of infection” label claim for Lepto hardjo-bovis — the highest label claim available, Dr. Linhart adds. And, BOVI-SHIELD GOLD FP 5 VL5 HB is fully supported by a Fetal Protection Guarantee for BVD PI-free calves and IBR abortion.**

“To help prevent LHB infection, the best time to vaccinate is early in the calf’s life,” Dr. Linhart says. “In addition to vaccinating cows, all heifers should also be vaccinated as young as possible to help prevent infection before they can pass it on to their herdmates.” 

Additionally, Dr. Linhart recommends annual vaccination against LHB. According to the product’s label directions, once cattle receive their initial vaccination series, generally the preferred time to administer annual vaccinations is four to six weeks prior to breeding.

“It’s important that producers follow all label directions and indications because vaccines can’t perform as expected if the timing of these vaccinations is off,” Dr. Linhart says. “Also, cattle need to be provided with proper nutrition in order for the vaccine to be most effective.”

Producers should work with their veterinarian to develop a reproductive vaccine program that will provide optimal results desired for their operation.

“Input and cattle prices are at all-time highs, so producers can’t afford to risk losing even one calf to this preventable disease,” Dr. Linhart says. “Lepto hardjo-bovis can negatively impact the fertility of the herd, and therefore, producers should take every precaution to help reduce the threat — starting with a complete reproductive vaccination program.”

About Pfizer Animal Health

Pfizer Animal Health, a business unit of Pfizer Inc., is a global leader in the discovery, development, manufacture and commercialization of animal health medicines and vaccines, with a focus on both livestock and companion animals. For more than 60 years, we have been committed to enhancing the health of animals and bringing solutions to our customers who raise and care for them. To learn more, visit www.pfizeranimalhealth.com.

For further information, Contact:
Jean Lonie 
Pfizer Animal Health 

Lindsey Langemeier
Bader Rutter

*Do not use in pregnant cattle (abortions can result) unless they were vaccinated, according to label directions, with any BOVI-SHIELD GOLD FP or PREGGUARD GOLD FP vaccine prebreeding initially and within 12 months thereafter. Do not use in calves nursing pregnant cows unless their dams were vaccinated within the past 12 months as described above. To help ensure safety in pregnant cattle, heifers must receive at least 2 doses of any BOVI-SHIELD GOLD FP or PREGGUARD GOLD FP vaccine with the second dose administered approximately 30 days prebreeding.

**The Pfizer Animal Health 100% BVD PI-Free Guarantee and the IBR Abortion Guarantee will be administered through Pfizer Animal Health – VMIPS (Veterinary Medical Investigations and Product Support) at 855-4AH-PFIZER (855-424-7349). Proof of purchase is required. Calves born to BVD PI-positive cows or heifers do not qualify for the guarantee.

1 Wikse SE, Rogers GM, Ramachandran S, et al. Herd prevalence and risk factors of Leptospira infection in beef cow/calf operations in the United States: Leptospira borgpetersenii Serovar Hardjo. Bovine Practitioner 2007;41(1):15-23.
2 Sanderson MW, Gnad DP. Biosecurity for Reproductive Diseases. Vet Clin North Am Food Anim Pract 2002;18(1):79-98.
3 Floyd JG. Leptospirosis in cattle. Alabama Cooperative Extension System. 1994. Available at: www.aces.edu/pubs/docs/A/ANR-0858/ANR-0858.pdf. Accessed June 15, 2012.



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