Spring Vaccinations Set Calves Up for Long-term Success

Focus on complete immunity for the calf with spring vaccinations 

It’s never too early to think about a calf’s respiratory health. The steps producers take this spring with young calves not only help protect them through grazing season, but can help prepare the calves for a more complete immune response with preweaning and weaning booster vaccinations.

“The goal for vaccinating calves in the spring is primarily geared toward limiting disease in the summer months, especially pneumonia when calves are on grass,” says Catherine Maguire, technical services veterinarian with Zoetis. 

Maguire says it is key to protect calves against viral diseases that cause respiratory challenges like bovine respiratory syncytial virus (BRSV), infectious bovine respiratory (IBR) disease and parainfluenza 3 (PI3). 

“Respiratory viruses are our primary concern. When we couple Inforce 3® with One Shot® BVD, we achieve comprehensive viral protection, in addition to Mannheimia haemolytica protection,” Maguire says. “And that first dose of vaccine for Mannheimia really helps improve the response to the second dose at preweaning when bacterial pathogens are a bigger threat.”

Inforce 3 has the unique ability to stimulate a comprehensive local and systemic immune response in very young calves, even when antibodies from their dam’s colostrum are still active. This helps Inforce 3 be effective in a wide-ranging age of calves at branding and turnout. 

Following springtime vaccination with an injectable modified-live combination vaccine, like Bovi-Shield Gold One Shot®, at preweaning or weaning, provides an additive and synergistic immune response for calves prior to entry into feedlots.

Research at North Dakota State University demonstrated a significant (p=0.006) immune response to BRSV in calves given Inforce 3 at approximately 74 days of age, and again when boosted 153 days later with Bovi-Shield Gold One Shot.1

Overall, spring calf vaccinations are the first step in giving calves a strong foundation to meet disease challenges in the future.

For more information on developing a comprehensive calf respiratory program, visit with your veterinarian or Zoetis representative, or go to BuildingHealthyHerds.com.

About Zoetis
As the world’s leading animal health company, Zoetis is driven by a singular purpose: to nurture our world and humankind by advancing care for animals. After nearly 70 years innovating ways to predict, prevent, detect, and treat animal illness, Zoetis continues to stand by those raising and caring for animals worldwide - from livestock farmers to veterinarians and pet owners. The company’s leading portfolio and pipeline of medicines, vaccines, diagnostics, and technologies make a difference in over 100 countries. In 2020, Zoetis generated revenue of $6.7 billion with ~11,300 employees. For more, visit www.zoetis.com

For more information, contact: 
Kathleen McGinty

Lori Maude
Bader Rutter



Mon–Fri, 8:30am–6:30pm ET

This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2022 Zoetis Services LLC. All rights reserved.