Once-daily treatment for canine atopic dermatitis
Delivers 6-in-1 parasite protection for cats
Valuable discounts, expert information, and tips
See how injectable medications offer value beyond the prescription
The first and only FDA-Approved veterinary antiemetic
The first long-lasting monoclonal antibody therapy for canine atopic dermatitis
Vaccination for the prevention of respiratory disease caused by BRSV
The beef industry’s No. 1 branded preconditioning program
Exclusive pricing program for Cattle producers
Outstanding protection against costly respiratory and reproductive diseases
Treatment and control of gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites
Innovative food safety products that help deliver a farm-to-fork solution for beef
The most comprehensive guarantee available
First and only FDA-approved antibiotic for horses that offers a full course of therapy in just two doses
Annual vaccination with CORE EQ INNOVATOR helps provide the protection your horse needs
Treats and controls encysted small strongyles, bots and roundworms. QUEST PLUS contains an additional active ingredient for efficacy against tapeworms
Patented and scientific method of determining fair service pricing to improve your clinic's profitability
Connect directly to valuable dairy management resources and experts
The most "veterinarian recommended" and "producer used" prostaglandin in the market
Delivers the peace of mind and profitability that come with no milk discard
Effective and convenient treatment for acute metritis in cattle
Working together to improve reproduction
One injection treats and controls swine respiratory disease for 7 days
Protect sows and gilts from costly breeding herd diseases — parvovirus, leptospirosis and erysipelas
The industry standard for in ovo technology.
Full automation solutions for hatchery automation
Prevention and control of necrotic enteritis, increased rate of weight gain and improved feed efficiency in poultry
for the prevention of coccidiosis in poultry
modified-live vaccine that helps poultry companies reduce their overall Salmonella load
Blood glucose monitoring system
Smart new diagnostics platform that can reinvent your in-house diagnostic routines
Detect Johne’s Disease with confidence in cattle and goat herds
Simple and effective detection of a deadly Feline Virus
Accurate, affordable and easy to use
Order Beef Genetics products online
Order Dairy Genetics products online
Delivers reliable predictions of genetic merit based on test results of core traits
Represents the latest advancement in Angus genotyping technology.
Register today to learn more
Become a more effective leader
Looking for a tailored experience?
Earn continuing education credits and stay current on industry developments with Zoetis’ convenient, on-demand learning solutions.
Veterinarians, Veterinarian Techs, Business Owners, and Farm Hands
Launch your veterinary career
Veterinarian Students and Recent Graduates
Animal health expertise and results-focused resources for high-performing teams and leaders.
Veterinarians, Dairy producers, Beef producers, Equine Specialists, Pork producers, Poultry producers, Managers, Business Owners and Staff
Home / NEWS & MEDIA / Wellness Trait Field Study Demonstrates Effectiveness of Clarifide® Plus
Peer-reviewed, multiherd study validates the effectiveness
of wellness traits to predict disease incidence in dairy cattle
PARSIPPANY, N.J., Sept. 11, 2017 — Dairy producers can confidently use Clarifide® Plus to better manage disease and improve herd profitability. First-year results from the Wellness Trait Field Study conducted by Zoetis and published online in the Journal of Dairy Science (published in press Aug. 30, 2017), demonstrate an association between direct genomic predictions for wellness traits from Clarifide Plus and associated disease outcomes.
Accurately predicting animals that have higher risk of disease is crucial to helping identify which animals will be more or less likely to be profitable genetically. The Dairy Wellness Profit Index® (DWP$®) can help determine which animals can be raised more efficiently to minimize labor and treatment costs and maximize profitability for the next generation. DWP$ includes mastitis and all other wellness traits, as well as production, reproduction and other economically important traits in the index.
“First-year results of the Wellness Trait Field Study provide clear evidence that the wellness trait standardized transmitting abilities (STAs) in Clarifide Plus will provide accurate estimates of future performance to help identify animals with different relative genetic risk for the wellness traits,” said Anthony McNeel, senior scientist, Global Genetics Technical Services, Zoetis. “Coupling these predictions with sound management practices, Clarifide Plus provides producers with a compelling opportunity to help decrease disease incidence and improve the profitability of their herd.”
First-year disease incidence results
The objective of this ongoing, multiherd, multiyear study is to estimate the association between genomic wellness trait predictions derived from Clarifide Plus and the occurrence of health events in commercial dairy cattle. The study includes Holstein females selected from 11 herds from major dairy regions across the U.S. Two-thirds of the cattle enrolled were heifers entering their first lactation and the remaining one-third observed were entering their second lactation.
Wellness trait STAs were used to rank and assign cows to percentile groups within herd and age groups: worst 25%, 26%-50%, 51%-75% and best 25%. First-year results from the Wellness Trait Field Study demonstrated the risks for six common lactating cow diseases, including mastitis, lameness, metritis, retained placenta, displaced abomasum and ketosis, were approximately two times greater in the worst 25% of animals compared with the best 25% of animals, with a range of 1.6 to 17 greater odds ratios.1 Cows in the best 25% based on their respective genetic trait herd rankings had 47% fewer cases of mastitis, 33% fewer cases of lameness, 45% fewer cases of metritis, 64% fewer retained placentas, 94% fewer displaced abomasums and 53% fewer cases of ketosis than cows in the worst 25%.1
Mastitis incidence and implications
Among these diseases, mastitis represents a very interesting case study given the significant impact it has on the industry. These results effectively mean that those cows in the best 25% need half as many mastitis tubes, half as much discarded milk, half the number of days in the hospital pen, half the time taking care of the cow and half the amount of losses in milk or animals as those in the worst 25%.1,*
The importance of evaluating wellness traits
“With the advent of several new genomic testing products and traits to the market, it’s important that our customers have transparency and science-based data to support their choices,” said Cheryl Marti, associate director, U.S. Marketing, Dairy Genetics and Reproduction, Zoetis. “Zoetis places a large emphasis on validation through research before and after products are commercially launched. The publication of the Wellness Trait Field Study and a previously published paper on the Clarifide Plus genetic evaluation in the January 2017 issue of the Journal of Dairy Science affirms Zoetis' commitment to Clarifide Plus. Putting product research to the test through the rigorous process of being peer-reviewed in a scientific journal provides a deeper level of transparency so producers can be confident in choosing Clarifide Plus.”
Marti explained that it’s important for producers to evaluate any new genetic trait through the lens of relevancy, accuracy and proven effectiveness.
About Clarifide® Plus
In response to industry needs for genetic improvement of Dairy Wellness traits, Zoetis launched Clarifide® Plus, the first commercially available, U.S.-based genomic test that provides reliable genetic assessments at an early age, in March 2016. Developed to help producers select, manage and reduce risk for costly health events, Clarifide Plus includes genomic predictions for wellness traits that provide direct indication of the genetic risk factors for six of the most common and costly animal health challenges on dairies.
Clarifide Plus derives genetic predictions based on data collected from millions of health records within U.S. commercial herds, so U.S. producers can be confident results will be relevant to their operations. Clarifide Plus predictions also are very accurate with average estimated reliability of 50% for the six disease traits in young animals.
For more information about the Wellness Trait Field Study or genomic testing with Clarifide Plus, check out an educational video on the Zoetis Genetics YouTube channel or contact your Zoetis representative. The Zoetis Genetics YouTube channel includes other helpful resources, including videos highlighting customers’ experience using Clarifide Plus.
Zoetis is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 60 years of experience in animal health, Zoetis discovers, develops, manufactures and markets veterinary vaccines and medicines, complemented by diagnostic products, genetic tests, biodevices and a range of services. Zoetis serves veterinarians, livestock producers and people who raise and care for farm and companion animals with sales of its products in more than 100 countries. In 2016, the company generated annual revenue of $4.9 billion with approximately 9,000 employees. For more information, visit www.zoetisUS.com.
For further information contact: Cheryl MartiZoetis608email@example.com
Kristina HopkinsBader Rutter262firstname.lastname@example.org
Download the Clarifide Plus logo.
Download a high-resolution photo of heifers.
*On a per cow basis
1 McNeel AK, Reiter BC, Weigel D, Osterstock J, Di Croce FA. Validation of genomic predictions for wellness traits in US Holstein cows. J Dairy Sci. 2017;100:1-10. doi: 10.3168/jds.2016-12323
Mon–Fri, 8am–8pm ET
You are leaving the country website to access another site in the group.
Regulatory constraints and medical practices vary from country to country. Consequently, the information provided on the site in which you enter may not be suitable for use in your country.
This site is intended for U.S. Animal Healthcare Professionals.
All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2017 Zoetis Services LLC. All rights reserved.