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Role Of NGF In OA Pain

Studies have identified a new key player in the transmission of pain associated with osteoarthritis (OA) in people, dogs and cats. In adults, Nerve Growth Factor (NGF) plays a significant role in pain signaling. Watch the video below to watch the newly identified mechanism of action of Nerve Growth Factor in OA pain.


NGF in Osteoarthritis Pain
Duncan Lascelles, BSc, BVSc, PhD, FRCVS, CertVA, CertSAS, discusses the clinical implications of NGF for osteoarthritis pain.


NGF in Central Sensitization
Duncan Lascelles, BSc, BVSc, PhD, FRCVS, CertVA, CertSAS, discusses the clinical implications of NGF for central sensitization.


Anti-NGF for Control of Pain in Dogs and Cats
Read a paper published in Veterinary Record (January 5, 2019) that reviews the science behind NGF and the potential veterinary treatments based on this novel pathway by Masataka Enomoto, BVSc.

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Other Resources

Anti-NGF monoclonal antibodies as a prospective new therapy for feline and canine osteoarthritis

Also published in the same issue of Veterinary Record is a short summary of the science behind anti-NGF monoclonal antibodies as a prospective new therapy for feline and canine osteoarthritis by Mark Epstein, DVM, Dipl. ABVP (Canine and Feline), CVPP.


Measuring pain in dogs and cats using structured behavioural observation

Providing insight for veterinarians and pet owners alike, Dr. Reid’s recent review paper highlights the tools available to measure pain in dogs and cats based on behavioral changes.



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