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(ceftiofur hydrochloride) Sterile Suspension

A one-day mastitis treatment isn’t a cure. It’s a treatment.


If you’re looking for a long-term solution to an age-old problem, there’s no such thing as a quick fix. SPECTRAMAST® LC is the only mastitis treatment product labeled for up to eight days of therapy. It helps cure mastitis with broad-spectrum coverage against modern pathogens, including Escherichia coli (E. coli).

SPECTRAMAST® LC Sterile Suspension is indicated for use in lactating dairy cattle for the following treatments:

1.) Clinical mastitis associated with:

  • coagulase-negative staphylococci
  • Streptococcus dysgalactiae
  • Escherichia coli and

2.) Diagnosed subclinical mastitis associated with:

  • coagulase-negative staphylo
  • Streptococcus dysgalactiae

SPECTRAMAST® LC Sterile Suspension is an oil-based sterile suspension. Each 10 mL PLASTET® Disposable Syringe contains 125 mg ceftiofur equivalents as the hydrochloride salt. Ceftiofur hydrochloride is a cephalosporin antibiotic.

To learn more about the flexibility of extended therapy protocols to help cure mastitis and to hear about the benefits from dairy producers and veterinarians firsthand, visit

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    • Once-a-day dosing—Convenient for producers and convenient for the milking crew.
    • Extended therapy—Its unique, flexible label allows you to treat for at least two and up to eight days to achieve a complete, or bacteriological, cure.
    • 72-hour milk withhold— Residue trials show that no matter how many days you decide to treat per label directions, milk is safe for human consumption after 72 hours post-last treatment.
    • 2-day pre-slaughter meat withdrawal— The shortest meat withhold time available provides more options for greater management and flexibility.
    • Piece of mind—SPECTRAMAST LC is backed by the Residue Free Guarantee*

    * Residue Free Guarantee: If you use a Zoetis-branded ceftiofur product according to label indications, and experience a violative ceftiofur milk or meat residue, Zoetis will compensate you for the beef market value of the animal or purchase the tanker of milk at fair market value. You must purchase the product from a Zoetis-approved supplier, use the product according to label indications, have documentation of the product purchase and treatment records, and have conducted training on appropriate use to ensure proper dose and route of administration of the product. Extra-label use as prescribed by a veterinarian is excluded from the guarantee. If you experience a ceftiofur residue violation after following label indications and the above steps, contact Zoetis VMIPS (Veterinary Medical Information and Product Support) at 800-366-5288 to report the situation.

  • Infuse one (1) syringe into each affected quarter. Repeat this treatment in 24 hours. For extended duration therapy, once daily treatment may be repeated for up to eight consecutive days.


    Disinfect teats thoroughly by removing obvious organic matter and dipping teats in a teat disinfectant approved by the NMC (National Mastitis Council). Dry teats thoroughly by using individual cow towels or paper towels. Milk out udder completely. Using an alcohol pad provided, wipe off the end of the affected teat using a separate pad for each teat. Choose the desired insertion length (full or partial) and insert tip into teat canal; push plunger to dispense entire contents; massage the quarter to distribute the suspension into the milk cistern.


    After successful treatment, reinfection may occur unless good herd management, sanitation and mechanical safety measures are practiced. Affected cows should be watched carefully to detect recurrence of infection and possible spread to other animals.

    SPECTRAMAST LC Sterile Suspension is available in cartons containing one (1) unbroken package of 12 – 10 mL PLASTET Disposable Syringes with 12 individually wrapped 70% isopropyl alcohol pads. Also available in pails of 144 syringes.

    Store at controlled room temperature 68 to 77° F (20 to 25° C). Protect from light. Store PLASTETS in carton until used.


People with known hypersensitivity to penicillin or cephalosporins should avoid exposure to SPECTRAMAST LC. Product requires a 72-hour milk discard period and a 2-day pre-slaughter withdrawal period following the last treatment. Use of this product in a manner other than indicated on the label, or failure to adhere to proper milk discard period, will result in violative residues.

SPECTRAMAST LC is intended for use in lactating dairy cattle only with the specified, labeled pathogens. To assure responsible antimicrobial drug use, it is expected that subclinical mastitis will be diagnosed using a positive culture, or other pathogen-specific test, in addition to any other, appropriate veterinary medical evaluation prior to treatment.

 Prescribing Information



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