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Paul H. Walz, DVM, MS, PhD, Diplomate, ACVIM
Professor and Coordinator, Animal Health Research Department of Pathobiology
College of Veterinary Medicine, Auburn University
Daniel W. Scruggs, DVM, Diplomate, ACVP
Managing veterinarian, Zoetis Technical Services
Based on the overall results, should I change to CATTLEMASTER GOLD? It looks like the protection was better.
Summary of Dr. Walz’s Reply: The results from this study indicate that both vaccination programs are highly efficacious. We did see better protection with the CATTLEMASTER GOLD FP revaccination program, but those weren’t statistically significant differences.
Does this mean I can expect the same results giving other all killed vaccines?
Summary of Dr. Scruggs’ Reply: None of the other killed vaccines have labels for fetal protection against IBR or BVD. There have been assertions that other killed vaccines will provide the same level of protection, but at some point they’re going to have to prove that before producers and veterinarians are going to invest the money.
What will happen three to four years down the road. What kind of protection might I anticipate if I stay on CATTLEMASTER GOLD FP and never use MLV in those cows after the heifer vaccination.
Summary of Dr. Walz’s Reply: Modified-live viral vaccines do a great job of stimulating both arms of the immune system. They stimulate antibody production but they also stimulate a cell-mediated immune response. Killed vaccines generally only stimulate a humoral, or antibody, response.
In our study, when we administered the inactivated BVD viral component and the temperature-sensitive modified-live viral component of CATTLEMASTER GOLD FP, we did stimulate tremendous humoral immunity in those animals. But what we don’t know is how well we’re stimulating the cell portion of the immunity.
Can I give a modified-live viral vaccine to the calves nursing pregnant cows vaccinated this way?
Summary of Dr. Scrugg’ Reply: According to label, if the nursing calf is to be administered a modified-live viral vaccine, that cow needs to have received the same modified-live viral vaccine within the previous 12 months. It’s really a call for the veterinarian overseeing the herd.
Depending on weather and other priorities, I find myself working heifers at different ages from those in the study. How wide is my window of opportunity to give them two doses of BOVI-SHIELD GOLD FP prior to breeding?
Summary of Dr. Scrugg’ Reply: The width of the time between vaccinations is not that important. The key vaccine for heifers is the dose that occurs 30 to 40 days prior to breeding. That’s the important dose in terms of efficacy and safety if that heifer’s going to receive BOVI-SHIELD GOLD FP as a pregnant cow.
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