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(dinoprost tromethamine injection)

Most-used prostaglandin in the market1

LUTALYSE® Injection (dinoprost tromethamine injection) is the most used prostaglandin in the market.1 Artificial insemination synchronization programs with LUTALYSE can improve breeding success. Producers and veterinarians today have more options for using LUTALYSE in reproduction programs than ever before. FACTREL® Injection (gonadorelin injection) is approved for use with LUTALYSE to synchronize estrous cycles in beef or dairy heifers and cows.

LUTALYSE is the only prostaglandin approved to be used with EAZI-BREED™ CIDR® Cattle Inserts in beef and dairy heifers and cows.

Zoetis is the world leader in cattle reproduction research and its products are supported by industry-leading sales and technical services.

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    • A synchronized breeding program with LUTALYSE can:
      • Improve pregnancy rates
      • Reduce time necessary for heat detection
      • Make more efficient use of labor
      • Reduce cull rates
    • No meat or milk withdrawal
    • Useful for controlled breeding
    • Dose size reduces problems if injection-site leakage occurs
  • Effective in animals having a functional corpus luteum in the following applications:

    • For estrus synchronization, inject 5 mL LUTALYSE intramuscularly (IM) either once or twice at 10- to 12-day intervals.
    • For treatment of unobserved estrus, inject a 5 mL dose IM. If estrus has not been observed by 80 hours after injection, breed at 80 hours; if the cow returns to estrus, breed at the usual time relative to estrus.
    • For postpartum treatment of pyometra, inject a dose of 5 mL IM at signs of pyometra (presence of a corpus luteum on the ovary and uterine horns containing fluid but not a conceptus based on palpation).

IMPORTANT SAFETY INFORMATION FOR LUTALYSE: Women of childbearing age and persons with respiratory problems should exercise extreme caution when handling LUTALYSE. LUTALYSE is readily absorbed through the skin and may cause abortion and/or bronchiospasms, therefore spillage on the skin should be washed off immediately with soap and water. Aseptic technique should be used to reduce the possibility of post-injection clostridial infections. Do not administer LUTALYSE in pregnant cattle unless cessation of pregnancy is desired. See full Prescribing Information.

IMPORTANT SAFETY INFORMATION FOR FACTREL: FACTREL is for use in cattle only. See full Prescribing Information.

IMPORTANT SAFETY INFORMATION FOR EAZI-BREED CIDR: Avoid contact with skin by wearing protective gloves when handling EAZI-BREED CIDR inserts. Do not use in heifers of insufficient size or age for breeding or in cattle with abnormal, immature, or infected genital tracts. Do not use inserts more than once.



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