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ONE SHOT® BVD

Respiratory protection from Mannheimia haemolytica and bovine viral diarrhea (BVD) Types 1 and 2 viruses in a single dose.

ONE SHOT BVD logo

ONE SHOT® BVD helps provide beef and dairy cattle with combined respiratory protection against Mannheimia haemolytica and bovine viral diarrhea (BVD) Types 1 and 2 viruses in a single dose.

When ONE SHOT BVD is used concurrently with INFORCE™ 3 respiratory vaccine:

  • Helps protect against bovine respiratory syncytial virus (BRSV), infectious bovine rhinotracheitis (IBR) virus, parainfluenza 3 (PI3) virus, M. haemolytica and BVD Types 1 and 2 viruses.
  • Helps young calves build the immunity they need prior to commingling of dairy calves and at turnout for beef calves.
  • Helps provide a convenient and effective way to combat bovine respiratory disease (BRD).
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  • ONE SHOT® BVD helps offer combined respiratory protection against Mannheimia haemolytica, the No. 1 calf killer,1,2 and bovine viral diarrhea (BVD) Types 1 and 2 viruses, two of the major respiratory viruses that cause bovine respiratory disease (BRD). It provides the same level of respiratory protection as ONE SHOT® and BOVI-SHIELD GOLD® BVD administered independently.

    Vaccine program for respiratory protection
    Used concurrently, a vaccine program that includes ONE SHOT BVD and INFORCE™ 3 respiratory vaccine:

    • Offers superior respiratory protection against bovine respiratory syncytial virus (BRSV) of INFORCE 3 with the complementary M. haemolytica and BVD protection of ONE SHOT BVD.
    • Offers an effective combination of antigens available for young calves — using the right antigens, at the right time, helps provide the immunity boost they need.
    • Helps provide comprehensive respiratory protection against BRSV, infectious bovine rhinotracheitis (IBR) virus, parainfluenza 3 (PI3) virus, M. haemolytica and BVD Types 1 and 2 viruses.

    Impact of respiratory disease on calves

    • BRD can negatively impact the health, productivity and profitability of a herd.
    • Young calves can easily fall victim to respiratory infections because of their underdeveloped immune systems and exposure to environmental stressors.
    • As the second-most significant disease impacting dairy operations3 and the leading cause of death in beef calves between three weeks of age and weaning,1 BRD can negatively impact the health, productivity and profitability of young calves.
  • Product Description: ONE SHOT® BVD is a freeze-dried preparation of modified-live virus (MLV) strains of bovine viral diarrhea (BVD) Types 1 and 2 viruses and product prepared from whole cultures of Mannheimia (Pasteurella) haemolytica propagated to increase the production of leukotoxin and capsular and cell-associated antigens. A sterile diluent, containing adjuvant to enhance the immune response, is provided to rehydrate the freeze-dried fraction.

    Label Claims: ONE SHOT BVD is for vaccination of healthy cattle to prevent viremia caused by BVD Types 1 and 2 viruses, and as an aid in preventing respiratory disease caused by BVD virus Types 1 and 2 and bovine pneumonia caused by Mannheimia haemolytica Type A1. A duration of immunity of at least 9 months has been demonstrated against BVD virus Types 1 and 2 respiratory disease.

    Packaging: 10- and 50-dose vials

  • ONE SHOT® BVD may be administered to pregnant cattle provided they were vaccinated, according to label directions, with any BOVI-SHIELD GOLD FP® or PREGGUARD® GOLD FP vaccine within the past 12 months. ONE SHOT BVD also may be administered to calves nursing pregnant cows provided their dams were vaccinated within the past 12 months as described above. To help ensure safety in pregnant cattle, heifers must receive at least 2 doses of any BOVI-SHIELD GOLD FP or PREGGUARD GOLD FP product with the second dose administered approximately 30 days prebreeding.

    General Directions: Vaccination of healthy cattle is recommended. Aseptically rehydrate the freeze-dried component with the sterile diluent provided, shake well, and administer 2 mL subcutaneously. In accordance with Beef Quality Assurance guidelines, this product should be administered in the neck region.

    Primary Vaccination: Administer a single 2 mL dose to healthy cattle. To avoid possible maternal antibody interference with active immunization, calves vaccinated before the age of 6 months should be revaccinated after 6 months of age or at weaning.

    Revaccination: Annual revaccination with a single dose is recommended. Good management practices support revaccination whenever subsequent stress or exposure is likely.

  • Precautions: Do not use in pregnant cows (abortions can result) unless they were vaccinated, according to label directions, with any BOVI-SHIELD GOLD FP® or PREGGUARD GOLD FP vaccine within the past 12 months. Do not use in calves nursing pregnant cows unless their dams were vaccinated within the past 12 months as described above. To help ensure safety in pregnant cattle. heifers must receive at least 2 doses of any BOVI-SHIELD GOLD FP or PREGGUARD GOLD FP product with the second dose administered approximately 30 days prebreeding,

    • Store at 2°C to 7°C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze.
    • Use entire contents when first opened.
    • Sterilized syringes and needles should be used to administer this vaccine.
    • Do not sterilize with chemicals because traces of disinfectant may inactivate the vaccine.
    • Burn containers and all unused contents.
    • Do not vaccinate within 21 days before slaughter.
    • Contains gentamicin as a preservative.
    • As with many vaccines, anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy.
    • This product has been shown to be efficacious in healthy animals. A protective immune response may not be elicited if animals are incubating an infectious disease, are malnourished or parasitized, are stressed due to shipment or environmental conditions or are otherwise immunocompromised, or if the vaccine is not administered in accordance with label directions.