Use the applicator for proper administration of Oti-Clens. Replace the bottle cap with the applicator tip provided. Apply liberally to the ear. Massage the base of the ear. Clean the accessible portion of the ear with a cotton ball. Repeat if necessary. Use once or twice weekly on a routine basis. Oti-Clens may be used up to 3 times daily over extended periods. Use as directed by your veterinarian.