REVOLUTION PLUS is the only 6-in-1 preventative with broad-spectrum action against parasites that threaten cats and kittens

Select a parasite to learn more

BUILDING ON THE TRUSTED LEGACY OF REVOLUTION® (selamectin)

Safe for cats and kittens as young as 8 weeks of age, weighing 2.8 lbs or greater
Simple-to-apply, quick-drying, small-volume, monthly topical solution
Helps protect the special bond between cats and their families; no separation required after applying

See the MOAs, or modes of action, behind the "PLUS"

Unique Dual Action

Selamectin and Sarolaner Deliver Even Broader Protection Against Parasites ...
With Unique Dual Action Against Fleas and Ear Mites

Selamectin MOA: kills parasites primarily through interference with their glutamate-gated chloride channels, causing paralysis and death of the target parasite
Sarolaner MOA: kills parasites primarily through interference with their GABA-gated chloride channels, causing increased nerve stimulation and death of the target parasite

REVOLUTION PLUS is a simple-to-apply, quick-drying, small-volume, monthly topical solution that protects against fleas (Ctenocephalides felis), ticks (black-legged or deer tick (Ixodes scapularis), Gulf Coast tick (Amblyomma maculatum) and American dog tick (Dermacentor variabilis)), ear mites (Otodectes cynotis), roundworms (Toxocara cati), hookworms (Ancylostoma tubaeforme), and heartworms (Dirofilaria immitis) for cats and kittens as young as eight weeks of age and weighing 2.8 pounds or greater.

REVOLUTION PLUS helps protect the unprotected:
Parasite ranges are expanding, and the threat is ongoing

Cats and kittens of every age and lifestyle (indoor-only, indoor/outdoor, outdoor-only) can
regularly come in contact with parasites and their health risks, yet…

82%

of reported
tickborne diseases
in humans were cases of Lyme disease

78%

of cat owners LEAVE
their veterinarian’s office without purchasing any flea, tick, or heartworm preventative*²

73%

of pet owners FORGOT
to administer flea and tick preventatives on time^†3

Protecting cats and kittens from parasites may also help safeguard their families

An unseen threat that hits close to home

Are pet owners aware of fleas underfoot?

*VetStreet pets purchasing FTH, 2015 (n=5638).

^†Dog owner flea and tick product study, March 15, 2016 (n=1507).

IMPORTANT SAFETY INFORMATION:

The safe use of REVOLUTION PLUS has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Sarolaner, one of the ingredients in REVOLUTION PLUS, is a member of the isoxazoline class, which has been associated with adverse reactions such as tremors, ataxia, and seizures. Reactions have occurred in cats with or without a history of neurologic disorders. In humans, REVOLUTION PLUS may be irritating to skin and eyes.

SEE PRESCRIBING INFORMATION >>

REVOLUTION PLUS is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. REVOLUTION PLUS kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations with Ixodes scapularis (black-legged tick), Amblyomma maculatum (Gulf Coast tick) and Dermacentor variabilis (American dog tick), the treatment and control of ear mite (Otodectes cynotis) infestations, and the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections for one month in cats and kittens 8 weeks and older, and weighing 2.8 pounds or greater.

REFERENCES >>

This site is intended for U.S. Animal Healthcare Professionals.

The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

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