- Noticeable patches of hair loss (as a result of nibbling or scratching)14
- Tiny crusts (miliary dermatitis) and reddened, irritated skin14
- Skin allergies14
- Anemia, especially in young kittens15
- May transmit harmful tapeworms and other common parasites to the cat14
- Cats may develop behavioral problems that result from the inflammation/irritation of flea infestations16
Select one of the most common feline parasites to learn about the protection for cats and kittens that covers them all
REVOLUTION PLUS is a simple-to-apply, quick-drying, small-volume, monthly topical solution that protects against fleas (Ctenocephalides felis), black-legged or deer ticks (Ixodes scapularis), Gulf Coast ticks (Amblyomma maculatum) and American dog ticks (Dermacentor variabilis), ear mites (Otodectes cynotis), roundworms (Toxocara cati), hookworms (Ancylostoma tubaeforme), and heartworms (Dirofilaria immitis) for cats and kittens as young as eight weeks of age and weighing 2.8 pounds or greater.
REVOLUTION PLUS kills fleas before they lay eggs and keeps killing for a full 5 weeks
STARTS KILLING FLEAS
WITHIN 6 HOURS
WITHIN 6 HOURS
Residual speed of kill maintained through day 28 during subsequent weekly infestations
- 100% REDUCTION in adult fleas-count for at least 35 days in TWO clinical trials against an existing infestation and weekly reinfestation
- INTERRUPTS THE FLEA LIFE CYCLE by killing fleas before they can lay eggs
- DECREASES SIGNS of flea allergy dermatitis
The dual action of REVOLUTION PLUS (sarolaner and selamectin) was highly effective against fleas; Revolution (selamectin) was less effective (<80%) against positive control (isoxazoline*)6,7
*The control isoxaline in these studies was fluralaner.
See the MOAs, or modes of action, behind the "PLUS"
Unique Dual Action
Selamectin and Sarolaner Deliver Even Broader Protection Against Parasites ...
With Unique Dual Action Against Fleas and Ear Mites
- Selamectin MOA: kills parasites primarily through interference with their glutamate-gated chloride channels, causing paralysis and death of the target parasite
- Sarolaner MOA: kills parasites primarily through interference with their GABA-gated chloride channels, causing increased nerve stimulation and death of the target parasite
REVOLUTION PLUS kills ticks for a full month8,9
Black-legged or Deer Tick
(Ixodes scapularis)
Photo: James Gathany, Centers for Disease Control and Prevention
Gulf Coast Tick
(Amblyomma maculatum)
Photo: Centers for Disease Control and Prevention
American Dog Tick
(Dermacentor variabilis)
Photo: James Gathany, Centers for Disease Control and Prevention
Explore tick descriptions and distribution
Image by Centers for Disease Control and Prevention
Distribution: Widely distributed across the eastern United States19
Description: Adults ≈ 3 mm long; males dark brown to black in color; females are orange to red behind the scutum20
Parasite ranges are expanding, and the threat is ongoing
Image by Centers for Disease Control and Prevention
Distribution: Coastal areas of the U.S. along the Atlantic coast and the Gulf of Mexico19
Description: ≈ 6 mm long; unfed females have a reduced dark brown scutum with silvery white posterior stripes; unfed males’ scutum covers the entire top of the tick and is dark brown, with interconnected ornamentation of silvery white lines21
Parasite ranges are expanding, and the threat is ongoing
Image by Centers for Disease Control and Prevention
Distribution: Widely distributed east of the Rocky Mountains. Also occurs in limited areas on the Pacific Coast19
Description: Brown to reddish-brown with gray/silver markings on the scutum. Unfed females are ≈ 5 mm long and males are ≈ 3.6 mm long. Females have a short scutum while the male scutum covers the majority of its dorsal surface22
Parasite ranges are expanding, and the threat is ongoing
REVOLUTION PLUS is highly effective against ear mites
REVOLUTION PLUS PROTECTS
AGAINST THE MOST COMMON PARASITES;
AGAINST THE MOST COMMON PARASITES;
Bravecto Plus leaves cats unprotected against ear mites, a common feline pest
See the unique dual mechanism of action of REVOLUTION PLUS
Unique Dual Action
Selamectin and Sarolaner Deliver Even Broader Protection Against Parasites ...
With Unique Dual Action Against Fleas and Ear Mites
- Selamectin MOA: kills parasites primarily through interference with their glutamate-gated chloride channels, causing paralysis and death of the target parasite
- Sarolaner MOA: kills parasites primarily through interference with their GABA-gated chloride channels, causing increased nerve stimulation and death of the target parasite
REVOLUTION PLUS is highly effective against roundworms and hookworms
NEARLY
100%
REDUCTION IN ROUNDWORM
(Toxocara cati) fecal egg count on Days 30 and 60 (dosed once monthly)11
99.4%
REDUCTION IN HOOKWORM
(Ancylostoma tubaeforme) fecal egg counts at 30 days and 99.7% at 60 days§11
Every cat needs year-round heartworm protection, but not all parasiticides are labeled for use in cats regardless of heartworm status
- According to CAPC, data suggests that cats are infected with juvenile worms at the same rate as dogs12
- Juvenile worms in cats are capable of causing severe lung damage, known as Heartworm-Associated Respiratory Disease (HARD)12and sudden death
- Adult heartworm infections are less common (10% the rate of dogs) but also cause HARD12
- REVOLUTION PLUS was 100% effective in preventing heartworm infections with Dirofilaria immitis, in two clinical studies
REVOLUTION PLUS may be administered to cats with adult heartworm infection.
DO YOU KNOW YOUR PATIENT'S HEARTWORM STATUS?
Learn about Heartworm-Associated Respiratory Disease (HARD) in cats and kittens
The HARD Facts
Heartworm-Associated Respiratory Disease (HARD) in Cats
- Over 25% of adult heartworm-infected cats had no signs of infection12
- However, 10% of infected cats died suddenly without other clinical signs12
- Signs of respiratory tract disease and vomiting were the most commonly represented clinical signs12
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