- Noticeable patches of hair loss (as a result of nibbling or scratching)10
- Tiny crusts (miliary dermatitis) and reddened, irritated skin10
- Skin allergies10
- Anemia, especially in young kittens11
- May transmit other parasites (eg, tapeworms) to the cat10
- Cats may develop behavioral problems that result from the inflammation/irritation of flea infestations12
REV UP Protection Inside and Out
REVOLUTION PLUS is a simple-to-apply, quick-drying, small-volume, monthly topical solution that protects against fleas (Ctenocephalides felis), ticks (black-legged or deer tick (Ixodes scapularis), Gulf Coast tick (Amblyomma maculatum) and American dog tick (Dermacentor variabilis)), ear mites (Otodectes cynotis), roundworms (Toxocara cati), hookworms (Ancylostoma tubaeforme), and heartworms (Dirofilaria immitis) for cats and kittens as young as eight weeks of age and weighing 2.8 pounds or greater.
REVOLUTION PLUS kills fleas before they lay eggs and keeps killing for a full 5 weeks
STARTS KILLING FLEAS
WITHIN 6 HOURS
WITHIN 6 HOURS
Residual speed of kill maintained through day 28 during subsequent weekly infestations.
- 100% REDUCTION in adult flea count for at least 35 days in TWO clinical trials against an existing infestation and weekly reinfestation
- INTERRUPTS THE FLEA LIFE CYCLE by killing fleas before they can lay eggs
- DECREASES SIGNS of flea allergy dermatitis
See the MOAs, or modes of action, behind the "PLUS"
Unique Dual Action
Selamectin and Sarolaner Deliver Even Broader Protection Against Parasites ...
With Unique Dual Action Against Fleas and Ear Mites
- Selamectin MOA: kills parasites primarily through interference with their glutamate-gated chloride channels, causing paralysis and death of the target parasite
- Sarolaner MOA: kills parasites primarily through interference with their GABA-gated chloride channels, causing increased nerve stimulation and death of the target parasite
REVOLUTION PLUS kills ticks for a full month
Black-legged or Deer Tick
(Ixodes scapularis)
Photo: James Gathany, Centers for Disease Control and Prevention
Gulf Coast Tick
(Amblyomma maculatum)
Photo: Centers for Disease Control and Prevention
American Dog Tick
(Dermacentor variabilis)
Photo: James Gathany, Centers for Disease Control and Prevention
Effective results sustained for up to 5 weeks for black-legged or deer tick and American dog tick‡
Explore tick descriptions and distribution
Image by Centers for Disease Control and Prevention
Distribution: Widely distributed across the eastern United States13
Description: Adults ≈ 3 mm long; males dark brown to black in color; females are orange to red behind the scutum14
Parasite ranges are expanding, and the threat is ongoing
Image by Centers for Disease Control and Prevention
Distribution: Coastal areas of the US along the Atlantic coast and the Gulf of Mexico13
Description: ≈ 6 mm long; unfed females have a reduced dark brown scutum with silvery white posterior stripes; unfed males’ scutum covers the entire top of the tick and is dark brown, with interconnected ornamentation of silvery white lines15
Parasite ranges are expanding, and the threat is ongoing
Image by Centers for Disease Control and Prevention
Distribution: Widely distributed east of the Rocky Mountains. Also occurs in limited areas on the Pacific Coast13
Description: Brown to reddish-brown with gray/silver markings on the scutum. Unfed females are ≈ 5 mm long and males are ≈ 3.6 mm long. Females have a short scutum while the male scutum covers the majority of its dorsal surface16
Parasite ranges are expanding, and the threat is ongoing
REVOLUTION PLUS is highly effective against ear mites
See the MOAs, or modes of action, behind the "PLUS"
Unique Dual Action
Selamectin and Sarolaner Deliver Even Broader Protection Against Parasites ...
With Unique Dual Action Against Fleas and Ear Mites
- Selamectin MOA: kills parasites primarily through interference with their glutamate-gated chloride channels, causing paralysis and death of the target parasite
- Sarolaner MOA: kills parasites primarily through interference with their GABA-gated chloride channels, causing increased nerve stimulation and death of the target parasite
REVOLUTION PLUS is highly effective against roundworms and hookworms
100%
REDUCTION IN ROUNDWORM
(Toxocara cati) fecal egg count on Days 30 and 60 (dosed once monthly)6
99.4%
REDUCTION IN HOOKWORM
(Ancylostoma tubaeforme) fecal egg counts at 30 days and 99.7% at 60 days6
In TWO clinical studies, REVOLUTION PLUS was 100% effective in preventing heartworm infections with Dirofilaria immitis
— Gary D. Norsworthy, DVM, DABVP (Feline), 2018 AAFP Conference
Every cat and kitten NEEDS heartworm protection
- According to CAPC, data suggests that cats are infected with juvenile worms at the same rate as dogs8
- Juvenile worms in cats are capable of causing severe lung damage, known as Heartworm-Associated Respiratory Disease (HARD)8 and sudden death
- Adult heartworm infections are less common (10% the rate of dogs) but also cause HARD8
Learn about Heartworm-Associated Respiratory Disease (HARD) in cats and kittens
The HARD Facts
Heartworm-Associated Respiratory Disease (HARD) in Cats
- Over 25% of adult heartworm-infected cats had no signs of infection9
- However, 10% of infected cats died suddenly without other clinical signs9
- Signs of respiratory tract disease and vomiting were the most commonly represented clinical signs9
