REVOLUTION® PLUS Prescribing Information

REVOLUTION® Prescribing Information

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REFERENCES

  1. VetStreet FTH Projection 2020; Canine and Feline Flea, Tick, Heartworm Market Share. February 2020. Data on file.
  2. Vetstreet Data Analytics 2018. Vetstreet - ZMR Pets Purchasing FTH. Data on file. Zoetis Inc.
  3. Dog owner flea/tick product study: executive summary & data sheet. March 15, 2016. Data on file. Zoetis Inc.
  4. Foster Rosenblatt Top Cat Pricing Research & Forecast. Data on file. Zoetis Inc.
  5. Indoor Cats Parasiticides Tracker: “Stock Up” survey; fielded on 5/21-6/5/2018. Data on file. Zoetis Inc.
  6. Dryden MW, Canfield MS, Bocon C, Phan L, Niedfeldt E, Kinnon A, Warcholek SA, Smith V, Bress TS, Smith N, Heaney K, Royal C, Normile D, Armstrong R, Sun F, In-home assessment of either topical fluralaner or topical selamectin for flea control in naturally infested cats in West Central Florida, USA. Parasites & Vectors. 11:422, 2018.
  7. Dryden MW, et al. Evaluation of a topical sarolaner-selamectin combination to control flea populations on naturally infested cats in private residences in West Central Florida. Vet Parasitol, 2020.
    http://doi.org/10.1016/j.vetpar.2020.109172.
  8. Study Report No. A186C-US-14-100. Data on file. Zoetis, Inc. 2014.
  9. Study Report No. A186C-US-14-106. Data on file. Zoetis, Inc. 2014.
  10. Study Report No. A186C-US-14-098. Data on file. Zoetis, Inc. 2014.
  11. Study Report No. A186C-US-14-166. Data on file. Zoetis, Inc. 2017.
  12. Companion Animal Parasite Counsel (CAPC), Heartworms; Available at: https://capcvet.org/guidelines/heartworm/. Accessed Aug. 21st, 2018
  13. Atkins CE, DeFrancesco TC, Coats JR, Sidley JA, Keene BW. Heartworm infection in cats: 50 cases (1985-1997). J Am Vet Med Assoc. 2000;217(3):355-358.
  14. Cat Owners – Fleas. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/fleas/. Accessed September 2018.
  15. Fleas – Cat. Companion Animal Parasite Council. Available at: https://www.capcvet.org/guidelines/fleas/. Accessed September 2018.
  16. Foil CS. Flea Allergy. Annual Dermatology Conference, Louisiana State University, December 11, 2005. Available at: http://www.lsu.edu/vetmed/veterinary_hospital/services/dermatology/ce_lectures/flea_allergy.php. Accessed June 2018.
  17. Study Report No. A186R-US-16-201. Data on file. Zoetis Inc.
  18. Bravecto® (fluralaner topical solution) for cats. Product information. Intervet Inc. (d/b/a Merck Animal Health), Madison, NJ; 2016.
  19. Geographic distribution of ticks that bite humans. Available at: https://www.cdc.gov/ticks/geographic_distribution.html. Accessed September 2018.
  20. Tick description. Available at: http://entnemdept.ufl.edu/creatures/URBAN/MEDICAL/Deer_tick.htm. Accessed September 2018
  21. Tick description. Available at: http://entnemdept.ufl.edu/creatures/urban/medical/gulf_coast_tick.htm. Accessed September 2018.
  22. Tick description. Available at: http://entnemdept.ufl.edu/creatures/urban/medical/american_dog_tick.htm. Accessed September 2018.
  23. Ticks – Cat. Companion Animal Parasite Council. Available at: https://www.capcvet.org/guidelines/ticks/. Accessed September 2018.
  24. Cat Owners – Ticks. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/ticks/. Accessed September 2018.
  25. Study Report No. A186R-US-17-215. Data on file. Zoetis Inc.
  26. Cat Owners – Ear Mites. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/ear-mites. Accessed September 2018.
  27. Gastrointestinal parasites of cats. Cornell University College of Veterinary Medicine. Available at: https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/gastrointestinal-parasites-cats. Accessed June 2018.
  28. Cat Owners – Roundworms. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/roundworms/. Accessed September 2018.
  29. Cat Owners – Hookworms. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/hookworms/. Accessed September 2018.
  30. Cat Owners – Heartworms. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/heartworms/. Accessed September 2018.
  31. Bravecto® Plus (fluralaner and moxidectin topical solution) for cats. Product information. Intervet Inc. (d/b/a Merck Animal Health), Madison, NJ; 2019.
  32. REVOLUTION® [package insert]. Kalamazoo, MI: Zoetis Inc; 2018.
  33. Advantage Multi® [package insert]. Shawnee Mission, KS: Bayer Animal Health; 2016.
  34. Frontline® Gold product label. Merial, Inc., Duluth, GA; 2013.

IMPORTANT SAFETY INFORMATION:

The safe use of REVOLUTION PLUS has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Sarolaner, one of the ingredients in REVOLUTION PLUS, is a member of the isoxazoline class, which has been associated with adverse reactions such as tremors, ataxia, and seizures. Reactions have occurred in cats with or without a history of neurologic disorders. In humans, REVOLUTION PLUS may be irritating to skin and eyes.

PRESCRIBING INFORMATION >>

REVOLUTION PLUS is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. REVOLUTION PLUS kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations with Ixodes scapularis (black-legged tick), Amblyomma maculatum (Gulf Coast tick) and Dermacentor variabilis (American dog tick), the treatment and control of ear mite (Otodectes cynotis) infestations, and the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections for one month in cats and kittens 8 weeks and older, and weighing 2.8 pounds or greater.

REFERENCES >>

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This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2021 Zoetis Services LLC. All rights reserved.