Protect cats with safe, effective 5‑in‑1 control.*

Proven efficacy. Proven safety. And a whole lot of purring.

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Veterinarians’ #1 Choice for Protection Against Fleas and Heartworms¹

Your patients deserve safe, proven protection. Your clients deserve a preventive that’s easy to administer and that they can trust. REVOLUTION^® (selamectin) scratches both those items off your list of concerns.

5-in-1 protection provides peace of mind

Protects against fleas, heartworms, roundworms, hookworms and ear mites.*

Easy to administer

Monthly topical application that dries quickly.

Flea and heartworm protection

Kills adult fleas and prevents flea eggs from hatching.*

Protects against heartworms* that lead to heartworm disease and heartworm associated respiratory disease (HARD).

Safe for the family and other pets

No separation period required after administration. REVOLUTION is safe in breeding, pregnant, lactating, and heartworm-positive cats and kittens 8 weeks and older.

IMPORTANT SAFETY INFORMATION:

Do not use REVOLUTION on sick, weak, or underweight cats. Use only on cats 8 weeks and older. Side effects may include digestive upset and temporary hair loss at application site with possible inflammation. In people, REVOLUTION may be irritating to skin and eyes. Wash hands after use. See full Prescribing Information.

*REVOLUTION protects cats against fleas (Ctenocephalides felis), heartworms (Dirofilaria immitis), roundworms (Toxocara cati), hookworms (Ancylostoma tubaeforme) and ear mites (Otodectes cynotis).

REFERENCES:

¹VetInsite^™ Analytics 2014. Zoetis Data on File.
²Dryden MW, Smith V, Payne PA, McTier TL. Comparative speed of kill of selamectin, imidacloprid, and fipronil–(S)-methoprene spot-on formulations against fleas on cats. Vet Ther. 2005;6(3):228-236.
³Dryden MW, Payne PA, Smith V. Efficacy of selamectin and fipronil–(S)-methoprene spot-on formulations applied to cats against adult cat fleas (Ctenocephalides felis), flea eggs, and adult flea emergence. Vet Ther. 2007;8(4);256-262.
⁴McCoy C, Broce AB, Dryden MW. Flea blood feeding patterns in cats treated with oral nitenpyram and the topical insecticides imidacloprid, fipronil and selamectin. Vet Parasitol. 2008:156(3-4):293-301.
⁵Atkins CE, DeFrancesco TC, Coats JR, et al. Heartworm infection in cats: 50 cases (1985-1997). J Am Vet Med Assoc. 2000;217(3):355-358.
⁶Blagburn BL, Dillon AR. Feline heartworm disease: solving the puzzle. Vet Med. 2007;102(3)(suppl):7-14.
⁷Heartworm basics. American Heartworm Society. https://www.heartwormsociety.org/pet-owner-resources/heartworm-basics. Accessed May 6, 2016.
⁸Levy JK, Snyder PS, Tavares LM, et al. Prevalence and risk factors for heartworm infection in cats from northern Florida. J Am Anim Hosp Assoc. 2003;39(6):533-537.
⁹Dillon AR, Tillson DM, Wooldridge A, et al. Effect of pre-cardiac and adult stages of Dirofilaria immitis in pulmonary disease of cats: CBC, bronchial lavage cytology, serology, radiographs, CT images, bronchial reactivity, and histopathology. Vet Parasitol. 2014;206(1-2):24-37.
¹⁰Zoonoses JF. Tracking ticks in the Netherlands. Vet Rec. 2006;158(7):217-218.
¹¹Current advice on parasite control: intestinal parasites - hookworms. Companion Animal Parasite Council. http://www.capcvet.org/capc-recommendations/hookworms. Accessed June 2, 2016.
¹²Six RH, Sture GH, Thomas CA, et al. Efficacy and safety of selamectin against gastrointestinal nematodes in cats presented as veterinary patients. Vet Parasitol. 2000;91(3-4):321-331.
¹³McTier TL, Shanks DJ, Wren JA, et al. Efficacy of selamectin against experimentally induced and naturally acquired infections of Toxocara cati and Ancylostoma tubaeforme in cats. Vet Parasitol. 2000;91(3-4):311-319.
¹⁴Six RH, Clemence RG, Thomas CA, et al. Efficacy and safety of selamectin against Sarcoptes scabiei on dogs and Otodectes cynotis on dogs and cats presented as veterinary patients. Vet Parasitol. 2000;91(3-4):291-309.
¹⁵Shanks DJ, McTier TL, Rowan TG. The efficacy of selamectin in the treatment of naturally acquired aural infestations of Otodectes cynotis on dogs and cats. Vet Parasitol. 2000;91(3-4):283-290.
¹⁶Current advice on parasite control: heartworm - feline heartworm. Companion Animal Parasite Council. http://www.capcvet.org/capc-recommendations/feline-heartworm. Accessed June 2, 2016.
¹⁷Nelson CT. HARD luck story: recognizing heartworm-associated respiratory disease. DX Consult. 2008;1(2):8-11.
¹⁸Yin S. Update on heartworm infection. Vet Forum (Veterinary Learning Systems). 2007;24(6):42-43.
¹⁹Dillon AR, Tillson DM, Wooldridge A, et al. Heartworm-associated respiratory disease (HARD): induction and reversibility relative to tissue larval stage and Wolbachia status. In: Heartworms Today; The Search for Solutions: Proceedings of the 2013 Triennial Symposium, New Orleans, LA, September 8-10, 2013. Wilmington, DE: American Heartworm Society; 2013:30-31.
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