- SIMBADOL (package insert), Florham Park, NJ, Zoetis, 2014.
- Data on file. Clinical Efficacy (Soft Tissue), 08-30-MC-D-CT-BP, and Clinical Efficacy (Orthopedic), 08-31-MC-D-CT-BP. Zoetis.
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- Freedom of Information Summary, NADA 141-434, SIMBADOL, July 18, 2014.
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INDICATION: SIMBADOL is indicated for the control of postoperative pain associated with surgical procedures in cats.
See References for detailed information about research studies referenced on this website.
IMPORTANT SAFETY INFORMATION: Due to serious human safety and abuse concerns, including physical or psychological dependence, life-threatening respiratory depression and additive CNS depressant effects, read the full prescribing information before using this drug, including the complete Boxed Warning. Not for use in humans. Hospital staff should be trained in the handling of potent opioids and should avoid accidental exposure. SIMBADOL has not been evaluated in breeding, pregnant, or lactating cats, in cats younger than 4 months of age or moribund cats. Do not use in cats with known hypersensitivity to buprenorphine hydrochloride or any of the components of SIMBADOL, or known intolerance to opioids. Use with caution in cats with impaired hepatic function. Adverse reactions may include hyperthermia, tachycardia, hypotension, hypertension, hypothermia, anorexia, and hyperactivity. For more safety information, refer to the full Prescribing Information.
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