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SPECTRAMAST LC® (CEFTIOFUR HYDROCHLORIDE)   STERILE SUSPENSION

THE SEVERITY OF MASTITIS MAY BE UNKNOWN, BUT THE TREATMENT ISN'T.

 

SPECTRAMAST LCUse the flexible treatment option of SPECTRAMAST® LC (ceftiofur hydrochloride) Sterile Suspension from two to eight days for the best chance that the mastitis is bacteriologically cured. Whether it’s a mild or stubborn case, SPECTRAMAST LC is the right product to take it on.

  • A clinical cure ≠ a bacteriological cure. A clinical cure, when milk appears normal, may not be the same as a bacteriological cure and may not equal treatment success. The udder and milk may look visibly better, but if bacteria still remain, the cow may relapse.
  • SPECTRAMAST LC doesn’t stop short. SPECTRAMAST LC provides flexible treatment for the best chance of a complete bacteriological cure against difficult pathogens.
  • Impact milk production. A complete bacteriological cure may mean more milk.

SPECTRAMAST® LC (ceftiofur intramammary suspension) Sterile Suspension is indicated for use in lactating dairy cattle for (1) the treatment of clinical mastitis associated with coagulase-negative staphylococci, Streptococcus dysgalactiae, and Escherichia coli and (2) the treatment of diagnosed subclinical mastitis associated with coagulase-negative staphylococci and Streptococcus dysgalactiae.

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  • Benefits of SPECTRAMAST LC include:

    • Convenient once-a-day dosing.
    • A 72-hour milk discard.
    • A two-day pre-slaughter meat withdrawal — the shortest withhold time available for greater management flexibility.
    • Optional on-label flexible label therapy to treat for two days and up to eight days to achieve a complete bacteriological cure.
    • A 70.4% bacteriological cure rate was achieved with just TWO syringes of SPECTRAMAST LC, according to research.1
  • A clinical cure ≠ a bacteriological cure

    • A clinical cure, when milk appears normal, may not be the same as a bacteriological cure and may not equal treatment success.
    • Achieving a bacteriological cure the first time helps prevent relapses, the labor and expense of re-treatments, chronic mastitis infections and mastitis spread.
    • The option of flexible label mastitis therapy from SPECTRAMAST LC helps tailor treatment duration to the individual case for mastitis when extra days of therapy are needed.
    • SPECTRAMAST LC gives you the flexibility to continue once-daily treatment for up to eight consecutive days for more stubborn mastitis cases and is the only mastitis product approved for additional treatments.

    The flexible label of SPECTRAMAST LC provides approved milk and slaughter withholds no matter how many days you need to treat per label directions. A Cornell University study evaluated the efficacy of SPECTRAMAST LC for treating mild and moderate cases of Gram-negative mastitis.2

    • Cows with complete cures gave 8.8 pounds more milk compared with cows not cured (P < 0.05).2
    • Bacteriological cure rate for quarters infected with Escherichia coli was 89% in cows treated with SPECTRAMAST LC versus 53% in cows receiving no treatment.2
  • Infuse one (1) syringe into each affected quarter. Repeat this treatment in 24 hours. For extended-duration therapy, once daily treatment may be repeated for up to eight consecutive days.

    Treatment:

    Disinfect teats thoroughly by removing obvious organic matter and dipping teats in a teat disinfectant approved by the NMC (National Mastitis Council). Dry teats thoroughly by using individual cow towels or paper towels. Milk out udder completely. Using an alcohol pad provided, wipe off the end of the affected teat using a separate pad for each teat. Choose the desired insertion length (full or partial) and insert tip into teat canal; push plunger to dispense entire contents; massage the quarter to distribute the suspension into the milk cistern.

    Reinfection:

    After successful treatment, reinfection may occur unless good herd management, sanitation and mechanical safety measures are practiced. Affected cows should be watched carefully to detect recurrence of infection and possible spread to other animals.

    SPECTRAMAST LC Sterile Suspension is available in cartons containing one (1) unbroken package of 12 10-mL PLASTET Disposable Syringes with 12 individually wrapped 70% isopropyl alcohol pads. Also available in pails of 144 syringes.

    Store at a controlled room temperature between 68 and 77° F (20 to 25° C). Protect from light. Store syringes in carton until used.

  • 1Data on file, Study Report No. a0091969, Pharmacia & Upjohn Animal Health.
    2Schukken YH, Bennett GJ, Zurakowski MJ, et al. Randomized clinical trial to evaluate the efficacy of a 5-day ceftiofur hydrochloride intramammary treatment on nonsevere Gram-negative clinical mastitis. J Dairy Sci. 2011;94(12):6203-6215.

 

IMPORTANT SAFETY INFORMATION
People with known hypersensitivity to penicillin or cephalosporins should avoid exposure to SPECTRAMAST LC. Product requires a 72-hour milk discard period and a 2-day pre-slaughter withdrawal period following the last treatment. Use of this product in a manner other than indicated on the label, or failure to adhere to proper milk discard period, will result in violative residues. To view the full Prerscribing Information, click here.

IMPORTANT DIAGNOSTIC INFORMATION 
SPECTRAMAST LC is intended for use in lactating dairy cattle only with the specified, labeled pathogens. To assure responsible antimicrobial drug use, it is expected that subclinical mastitis will be diagnosed using a positive culture, or other pathogen-specific test, in addition to any other, appropriate veterinary medical evaluation prior to treatment.

SPM-00071