APOQUEL® targets specific cytokines that cause itch and inflammation in allergic skin disease, relieving symptoms with minimal impact on the immune system
How does APOQUEL work?
APOQUEL has minimal effect on JAK2-dependent cytokines involved in hematopoiesis and innate immunity
APOQUEL is not a corticosteroid, antihistamine or cyclosporine
Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.
Important Safety Information
Do not use APOQUEL in dogs less than 12 months of age or those with serious infections. APOQUEL may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. APOQUEL has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporine. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. APOQUEL has been used safely with many common medications including parasiticides, antibiotics and vaccines.
For more information, please see the full Prescribing Information.
References: 1. Gonzales AJ, Fleck TJ, Humphrey WR, et al. IL‐31‐induced pruritus in dogs: a novel experimental model to evaluate anti‐pruritic effects of canine therapeutics. Vet Dermatol. 2016;27(1):34-e10. doi:10.1111/vde.12280. 2. Marsella R, Sousa CA, Gonzales AJ, et al. Current understanding of the pathophysiologic mechanisms of canine atopic dermatitis. J Am Vet Med Assoc. 2012;241(2):194-207. doi:10.2460/javma.241.2.194.
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