The following materials provide an overview of allergic skin disease and highlight the results of studies in which APOQUEL® was administered:
- Cosgrove, Cleaver (DOF A75 data)
An open-label compassionate-use study of up to 4 months of APOQUEL treatment (n=247). The study assessed long-term safety, efficacy and quality of life in treated dogs.
- Gadeyne, Little (DOF 096 data)
A randomized, single-blind 28-day study comparing the efficacy and safety of APOQUEL vs prednisolone treatment (n=123).
- Little, King, Davis (DOF 025 data)
A blinded, randomized trial comparing the safety and efficacy of APOQUEL vs cyclosporine (n=226).
- Gonzales, Bowman, Fici (now published, was in press)
An in vitro trial demonstrating the ability of APOQUEL to selectively inhibit JAK-1 cytokines implicated in allergy, inflammation and pruritus.
- A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (APOQUEL) in client-owned dogs with atopic dermatitis
Link to the published results of the clinical trial studying client-owned dogs with atopic dermatitis who were administered APOQUEL.
- APOQUEL technical monograph
A comprehensive overview of the science of allergic skin disease and APOQUEL, including all of its pharmacologic properties and results of clinical trials.
- The short-term and long-term side effects of steroids
A 1-page chart that illustrates all the different ways steroids can affect dogs after acute and chronic use.
PET OWNER MATERIALS
Resources for pet owners who are considering or who have dogs taking APOQUEL:
Research and development colleagues at Zoetis present data from their studies on APOQUEL:
- APOQUEL is a targeted therapy
Dr. Andrea Gonzales reviews the mechanism of action for APOQUEL. (12:00)
- APOQUEL and allergy testing
Dr. Andrea Gonzales reviews how APOQUEL can work in combination with allergy testing. (3:52)
- APOQUEL for the treatment of allergic dermatitis
Dr. Sallie Cosgrove reviews the clinical trials evaluating APOQUEL in the treatment of allergic dermatitis in dogs. (13:02)
- APOQUEL for the treatment of allergic dermatitis
APOQUEL control of atopic dermatitis Dr. Sallie Cosgrove presents the results of the clinical trial evaluating the use of APOQUEL for the treatment of canine atopic dermatitis. (16:22)
- Continuation therapy
Dr. Sallie Cosgrove discusses the results of the continuation therapy study that allowed dogs to be treated with APOQUEL for more than 2 years. (8:03)
- Non-clinical safety evaluation of APOQUEL
Dr. Phillis Malpas unveils the results of a study conducted on the safety of APOQUEL in a controlled laboratory setting before it was tested in the field. (21:15)
- Pharmacokinetics and ADME (absorption, distribution, metabolism and elimination) of APOQUEL
Dr. Wendy Collard presents the results from a series of studies that evaluated APOQUEL and its relationship to pharmacokinetics and pharmacodynamics. (6:24)
- Breaking the cycle of canine pruritus
A panel of experts in the field of veterinary medicine discuss the limitations of current therapies and share their experiences with APOQUEL. (1:34:12)
Veterinarians and pet owners share their personal experiences with APOQUEL:
- The unassuming hero
Veterinary dermatologist Tiffany Tapp discusses her experience with APOQUEL in a client’s dog, Keaura, and how this changed their lives forever.
- APOQUEL from a dermatologist‘s and owner‘s perspective
Veterinary dermatologist Lindsay McKay and the owners of 2 dogs share their experiences with APOQUEL and all the different ways it has affected their lives.
please visit www.ItchCycle.com
Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.
Important Safety Information
Do not use APOQUEL in dogs less than 12 months of age or those with serious infections. APOQUEL may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. APOQUEL has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporine. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. APOQUEL has been used safely with many common medications including parasiticides, antibiotics and vaccines.
For more information, please see the full Prescribing Information.
The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.
All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted.
© 2017 Zoetis Services LLC. All rights reserved. APQ-00371
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