ABOUT CLAVAMOX® (amoxicillin trihydrate/clavulanate potassium)
- The veterinary antibiotic trusted for over 30 years1
- Potentiated penicillin approved for veterinary use in dogs and cats
- Combines the broad-spectrum antibiotic activity of amoxicillin with the unique β-lactamase-inhibiting effect of clavulanate potassium for antimicrobial activity
- Activity against many Gram-positive and Gram-negative aerobic and anaerobic bacteria
- Effective in treating skin infections in dogs and cats, periodontal infections in dogs and urinary tract infections in cats
- Available in chewables and drops
Mode of Action
This unique dual mode of action is what makes CLAVAMOX so effective
Bacteria protected by the β-lactamase enzyme
Clavulanic acid inhibits β-lactamase, thus allowing amoxicillin to disrupt cell wall integrity
Compromised cell wall causes swelling and eventual rupture, ultimately resulting in death of the bacteria
How it works, is why it works
- Many common bacteria are protected by the ß-lactamase enzyme that binds to and inactivates many penicillins and cephalosporins
- Amoxicillin alone is unable to inhibit ß-lactamase
- Clavulanic acid (clavulanate potassium) permanently inhibits ß-lactamase
- Once the ß-lactamase is neutralized, amoxicillin disrupts cell wall integrity
- Proven effective 4-to-1 ratio of amoxicillin trihydrate to clavulanic acid
- Four-quadrant activity provides broad-spectrum coverage you can trust
INDICATIONS FOR DOGS
- Skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp. and Escherichia coli.
- Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.
INDICATIONS FOR CATS
- Skin and soft tissue infections such as wounds, abscesses, cellulitis/dermatitis due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., Escherichia coli and Pasteurella spp.
- Urinary tract infections (cystitis) due to susceptible strains of Escherichia coli.
DOSAGE & ADMINISTRATION
Please refer to the full Prescribing Information for complete dosage and administration information.
IMPORTANT SAFETY INFORMATION: People with known hypersensitivity to penicillin or cephalosporins should avoid exposure to CLAVAMOX. Do not use in animals with a history of allergic reactions to penicillins or cephalosporins. See full Prescribing Information.
Antibiotic resistance and principles of treatment in veterinary dermatology. Expert advice on antibiotic selection and use in general practice.
Skin and Soft Tissue Infections
Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis (antimicrobial guidelines working group of the International Society for Companion Animal Infectious Diseases).
Urinary Tract Infections
Better taste, less waste: A renewed focus on chewable medications can increase product sales, generate additional profits, and promote client compliance.