Unique mechanism of action, long-lasting effect
The question of subtherapeutic concentrations & resistance
All antibiotics have subtherapeutic concentrations during the dosing interval.
- Poor compliance with oral medications can prolong these subtherapeutic concentrations.
Bacteria are either sensitive or resistant to an antibiotic.
- Following treatment, all susceptible bacteria are killed, selecting for the resistant bacteria.
- An antibiotic is not expected to have any effect on resistant organisms. This is true for all antibiotics.
With regard to antimicrobial resistance, the veterinary literature regarding Staphylococcus pseudintermedius and E. coli does not indicate that any antibiotic or class of antibiotics is more likely to result in resistance. It is the use of antibiotics in general.17-31
Zoetis supports the responsible use of antibiotics in animals and people.
Learn about our commitment to antibiotic stewardship »
IMPORTANT SAFETY INFORMATION: People with known hypersensitivity to penicillin or cephalosporins should avoid exposure to CONVENIA. Do not use in dogs or cats with a history of allergic reactions to penicillins or cephalosporins. Side effects for both dogs and cats include vomiting, diarrhea, decreased appetite/anorexia and lethargy. See full Prescribing Information.
* From these average half-lives, the expected elimination is 27–35 days for most animals. In 1 radiolabeled study, however, a very small number of cats were identified as having a detectable half-life of up to 13 days. Therefore, the following is included in the full prescribing information notes: “CONVENIA may persist in the body for up to 65 days.”
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