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CYTOPOINT™ is effective, even in dogs with challenging comorbidities1

EXELAND, male, age 9 years, Labrador Retriever

Veterinarian: Dr Lisa Reiter, University of Minnesota College of Veterinary Medicine, Minneapolis, MN

Exeland suffers from both blastomycosis and atopic dermatitis

Presentation and history

Exeland had suffered all his life from chronic year-round atopic dermatitis, with severe seasonal exacerbations. Antihistamines, glucocorticoids (oral and injectable), cyclosporine, allergen-specific immunotherapy and a strict elimination diet had failed to control his disease.

Exeland’s clinical picture became more complicated when he was diagnosed with blastomycosis with severe pulmonary and ocular infiltration and secondary bacterial pneumonia. He was prescribed various antifungals, including itraconazole, parenteral amphotericin B and voriconazole.

When Exeland presented to Dr Reiter, he had generalized superficial bacterial folliculitis and bilateral Malassezia otitis. He was receiving 10 mg prednisone every other day; despite this, Dr Reiter rated his pruritus 10/10.

Owner’s perspective

Exeland’s owner has a debilitating condition that affects his manual dexterity and makes regular pilling challenging, and Exeland’s treatments and illness were becoming both mentally and physically overwhelming for him. For both owner and dog, Exeland’s refractory itch was having a severe negative impact on quality of life.

Exeland remained controlled for nearly 3 months after one injection

Treatment decision

Exeland’s treatment team was reluctant to increase the prednisone dose above 10 mg every other day due to Exeland’s systemic fungal disease. Because of Exeland's serious infection, a number of potential treatments were contraindicated. Dr Reiter decided to give Exeland an injection of CYTOPOINT.

Treatment result

Exeland’s owner called 2 days after the initial injection to report that Exeland’s itch was a 0/10. Exeland’s itch remained controlled for nearly 3 months after the first injection. Dr Reiter reports that Exeland’s blastomycosis continues to improve clinically and his blastomyces antigen urine titer continues to decrease. Exeland has remained free of skin and ear infections.

“This drug truly saved both [the owner’s] and my patient’s lives! I don’t know what I would have done without having access to this amazing drug. Thank you, Zoetis!”

— Dr Lisa Reiter, 6/30/16

Indication: CYTOPOINT aids in the reduction of clinical signs associated with atopic dermatitis in dogs.

Reference: 1. Data on file, CYTOPOINT Case Studies, Zoetis LLC.

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