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Reliable heartworm treatment. Now with reliable availability.

New from Zoetis

DIROBAN (melarsomine dihydrochloride)



Now You Have a Reliable Supply

  • In recent years, melarsomine dihydrochloride, the preferred method for treating canine heartworm disease, has been in short supply.1
  • Your preferred heartworm treatment is now available to you, your clients and your heartworm-positive patients.
  • Recommended by the American Heartworm Society and Companion Animal Parasite Council over the use of monthly macrocyclic lactones for heartworm disease treatment.2-3

Slow Kill Treatment

Why Slow Kill Is the Inferior Treatment

  • The American Heartworm Society does not recommend slow kill as a treatment of heartworm disease.2
  • The longer adult worms are present, the longer pathology continues to develop. Treatment with DIROBAN will shorten the duration of infection by months or even years.
  • Up to 20% of heartworm-infected dogs continue to have persistent circulating microfilaria.4
    • Those dogs act as reservoirs for other dogs living nearby.4
  • With the slow kill treatment, dogs should be restricted from activity for up to 2 years;5 when treating with DIROBAN, the recommended period of restricted activity is only 12 weeks.2
  • Slow kill requires 100% pet owner compliance of monthly dosing for the duration of treatment up to 2 years.5 With DIROBAN, only 2 to 3 veterinary-administrated doses are required during treatment.6 When compliance is a top concern, why take the risk?


A Product You Know, a Company You Can Rely On

  • The active ingredient in DIROBAN, melarsomine dihydrochloride, is safe and effective in all dogs with Class 1, 2 and 3 heartworm disease.6
  • Laboratory and clinical field trials demonstrate that treatment with melarsomine dihydrochloride reduces and/or clears Dirofilaria immitis infection in dogs with Class 1, 2 and 3 heartworm disease.6
Diroban Efficacy Chart


You Should Always Have Access to Your First Choice

  • Recommended by the American Heartworm Society and Companion Animal Parasite Council.2‑3
  • The sooner adult and immature worms are killed, the sooner your patient and client return to their normal lives.
  • Helps preserve the human-animal bond by shortening the recovery time over slow kill.

DIROBAN provides pet owners with unprecedented support to help educate and manage heartworm treatment expectations.