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A single injection begins reducing itch within 1 day and continues working for a full month
OVER 80% OF DOGS HAD SUCCESSFUL PRURITUS REDUCTION AT DAY 3
At day 3, greater than 80% of dogs administered Canine Atopic Dermatitis lmmunotherapeutic* achieved treatment success, predefined as owner-assessed ≥20mm reduction in pruritus as scored on the pruritus Visual Analog Scale (VAS).1†
Mean pruritus scores were very mild to mild starting at day 1 and continuing for a full month
At day 42, owner assessment of pruritus VAS scores remained mild at 37.6 mm (mean baseline, 71.0 mm) for dogs receiving a 2 mg/kg dose of Canine Atopic Dermatitis Immunotherapeutic.1*
*This product license is conditional. Efficacy and potency test studies in progress.
†VAS is an owner-assessed scale that measures itch along a continuum from normal dog (no itch) to extremely severe itch, using numbers from 0-100. VAS scoring instruments were given to owners, accompanied by explanations of how to rank itch, based on the behavior of the animal. Owners ranked itch daily.
Reference: 1. Data on file, Study Report No. C863R-US-12-018. Zoetis LLC.
Skin condition begins to improve within 7 days
SKIN CONDITION SCORE REDUCTION WAS SIGNIFICANT AT DAY 14
Significantly more dogs treated with Canine Atopic Dermatitis Immunotherapeutic achieved treatment success (at least a 50% reduction from baseline in CADESI-03) compared to dogs treated with placebo from day 14 of the study.
Skin condition score reduction was maintained through day 28
Significant improvement in skin condition was noted at the first visit on day 7 (p≤0.05). At day 28, there was a nearly 50% decrease in mean CADESI-03 scores for dogs administered Canine Atopic Dermatitis Immunotherapeutic* (73.7) compared to dogs administered placebo (121.9) (mean baseline for all dogs, 153.9).1
*This product license is conditional. Efficacy and potency test studies in progress.
†Canine Atopic Dermatitis Extent and Severity Index. CADESI-03 skin condition assessment consisted of an evaluation of erythema, lichenification, excoriation and alopecia at 62 body sites.
Reference: 1. Data on file, Study Report No. C863R-US-12-018. Zoetis LLC.
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