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ProHeart(R) 12 (moxidectin)ProHeart(R) 12 (moxidectin)

ONE BITE* can give a dog heartworm disease. ONE PROHEART® 12 injection ensures ONE FULL YEAR of constant protection.

ProHeart 12 Is the Only Vet-Administered Injection to Prevent Heartworm Disease in Dogs for ONE Full Year

    In 3 well-controlled studies, ProHeart 12 showed 100% efficacy against Dirofilaria immitis.
    One ProHeart 12 injection puts compliance in your control.
    With no monthly doses for dog owners to remember, there are no gaps in protection.


83% of dog owners were “very interested” or “quite interested” in ProHeart 121
Stock photo of Opera House in Sydney, Australia

#1Prescribed Heartworm Preventative in Australia

Since 2000, doctors have administered ProHeart 12 in Australia, the second-largest canine heartworm market in the world.

Known in Australia as ProHeart SR-12.

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If you’re already certified to administer ProHeart 6® (moxidectin), you do not need to recertify for ProHeart 12.

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For patients you prefer to see twice a year, or for dogs 6 to 12 months of age, ProHeart 6 offers complete heartworm disease protection with 2 injections a year. Read More »

*From an infected mosquito.
Dirofilaria immitis.

IMPORTANT SAFETY INFORMATION: Use PROHEART 6 in dogs 6 months of age or older and PROHEART 12 in dogs 12 months of age or older. Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug. Hypersensitivity reactions may occur in some dogs when PROHEART is administered alone or with vaccines. Anaphylactic and anaphylactoid reactions can result in death and should be treated immediately with the same measures used to treat hypersensitivity reactions to vaccines and other injectable products. Reported side effects in clinical trials included vomiting, lethargy, diarrhea, anorexia, and hypersensitivity reactions. People should avoid inhalation, contact with eyes, or accidental self-injection. Certification is required before veterinarians and staff administer these products. See full Prescribing Information for PROHEART 6 and PROHEART 12, attached.

Reference: 1. Market Research and Forecast Development. Data on file. Zoetis, Inc.

The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

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