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Frequently Asked Questions

Find answers to common questions about ProHeart® 6 (moxidectin).

General

Who can purchase or administer ProHeart 6?

Veterinarians must be ProHeart 6 certified before they can purchase ProHeart 6. Only ProHeart 6–certified veterinarians and veterinary technicians and assistants can administer it. Veterinary technicians and assistants must be under the direction of a ProHeart 6–certified veterinarian. Veterinarians and veterinary staff can take the free 20-minute certification course at any time.

What is the efficacy of ProHeart 6?

In two notable clinical effectiveness trials, ProHeart 6 demonstrated 100 percent efficacy.2 Learn more about efficacy.

What is the mode of action (MOA) of ProHeart 6?

ProHeart 6 has a unique MOA. Slow-dissolving microspheres contain and prolong the effects of moxidectin—which redistributes from plasma to adipose tissue. The adipose tissue acts as a reservoir, allowing six months of efficacy. See a video demonstrating the MOA.

Where can I find resources about ProHeart 6 to share with my staff and clients?

Our Practice Resources include guides and charts for your staff, plus the 6 Months 1 Dose Toolbox: materials for your social media pages and website, video loops and print items.



Safety

Are there any age restrictions for patients being administered ProHeart 6?

ProHeart 6 has been evaluated and found safe in puppies and dogs ≥6 months. There is no upper age restriction in healthy dogs. See the Prescribing Information.

Is ProHeart 6 safe in special populations?

ProHeart 6 has been evaluated and found safe in pregnant and lactating females and breeding males, ivermectin-sensitive Collies and puppies ≥6 months of age. Get more information about safety and ProHeart 6.

IMPORTANT SAFETY INFORMATION: PROHEART 6 should be used in healthy dogs. Do not administer to sick, debilitated, underweight dogs or dogs that have a history of weight loss. Prior to administration, PROHEART 6 certified veterinarians should continue to assess patient health through a medical history, physical examination and if deemed appropriate, diagnostic testing. Continue to use caution when administering PROHEART 6 concurrently with vaccinations. Adverse events, including anaphylaxis, have been reported following the concomitant use of PROHEART 6 and vaccines. In some cases, anaphylactic reactions have resulted in death. Use with caution in dogs with pre-existing or uncontrolled allergic disease (food allergy, atopy or flea allergy dermatitis). Dogs receiving PROHEART 6 should be tested for existing heartworms as per the product label. In people, avoid PROHEART 6 contact with eyes. If contact with the eyes occurs, rinse thoroughly with water for 15 minutes and seek medical attention immediately. PROHEART 6 is available only to veterinarians through a restricted distribution program. Only certified veterinarians and staff can administer it. To obtain additional information including a copy of the product labeling, click here or call 1-888-ZOETIS1 (963-8471).
  1. Data on file. ProHeart 6 Freedom of Information Summary, NADA 141-189.

CONTACT US

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This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

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