Directions: Aseptically rehydrate the freeze-dried vaccine (Vanguard L4) with the sterile gel provided, shake well, and administer 1 mL subcutaneously or intramuscularly. Healthy dogs should receive 2 doses administered 3-4 weeks apart. Annual revaccination with a single dose is recommended.
1. Stokes JE, Kaneene JB, Schall WD, et al. Prevalence of serum antibodies against six Leptospira serovars in healthy dogs. J Am Vet Med Assoc 2007;230:1657-1664.
Precautions: Store at 2°-7°C. Do not freeze. Use entire contents when first opened. Sterilized syringes and needles should be used to administer this vaccine. Contains gentamicin as preservative. Vaccination of pregnant bitches should be avoided. In case of anaphylaxis, administer epinephrine or equivalent.