VANGUARD® Rapid Resp 2 Intranasal Canine Infectious Respiratory Disease (CIRD) Background Infectious respiratory disease in the dog is multifactorial, both bacterial and viral pathogens are frequently observed. The clinical signs will often be identical regardless of the infecting pathogen. Additionally, when respiratory diagnostic testing is performed in symptomatic dogs co-infections are often observed. The presence of multiple pathogens may lead to more severe symptoms. A multivalent immunization protocol can help PREVENT THE PREVENTABLE.