No Refrigeration WITNESS® Heartworm has a 12-month shelf life at room temperature (versus only 90 days for a leading competitor’s test).
No Snapping RIM™ (Rapid Immuno Migration) technology allows for a one-step process, as opposed to the ELISA method. So unlike with other in-house tests, you don’t lose time waiting to snap. Plus, you only need one drop of sample (anticoagulated whole blood, serum, or plasma).
Rapid Results With accurate results in approximately minutes you can give your clients the immediate test results they want and get your patients on a heartworm preventive sooner.
Easy to Interpret You get simple-to-understand results, with no complex interpretation needed:
One line on the right = negative
Two lines = positive
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WITNESS® Heartworm detects the presence of adult Dirofilaria immitis antigens in dog or cat blood. The WITNESS® format is referred to as Rapid Immuno Migration (RIM™). This technology is also sometimes referred to as lateral flow or rapid immunochromatography. WITNESS® tests perform well without refrigeration using an antigen-specific antibody labeled with colloidal gold.
After the sample and buffer are added to the sample pad (window 1), any antigens in the sample migrate across a nitrocellulose membrane along with the gold-labeled antibody (conjugate) and form an antigen/antibody gold complex. A second antibody specific to the antigen binds the antigen/antibody gold complex at the test line.
In a positive sample, this generates a pink to purple colored reaction line in window 2. Excess colloidal gold migrates across to the control line, where an antibody directed to the gold-labeled antibody binds to it. This causes formation of a colored control line (window 3).
A test result should always be interpreted in the context of all available clinical information and history for the dog or cat. Cats testing negative for heartworm antigen may benefit from other diagnostic tests, including heartworm antibody assays.