



What is Leptospirosis?
The Story of LEPTO EQ INNOVATOR®
Equine leptospirosis is a costly and underdiagnosed disease that can affect the entire equine industry. A recent nationwide study showed 75% of healthy horses were exposed to at least one leptospiral serovar.1
Leptospirosis is a bacterial infection caused by spirochetes belonging to Leptospira spp. Leptospira interrogans serovar Pomona, known as L. pomona, is most often associated with leptospirosis infections in horses in North America.2
L. pomona can colonize in the kidneys, be shed in the urine and cause horses to become septicemic.2 The bacteria are then circulated in the blood and can cause uveitis, or moon blindness (the most common cause of blindness in horses), as well as abortions and kidney failure. Kidney failure, especially in yearlings, can occur with renal infection associated with leptospirosis.1-3
Horses can become infected with leptospires through contact with urine from wildlife, cattle and dogs. Standing water and rainfall can pose an increased risk.
LEPTO EQ INNOVATOR® is the first and only leptospirosis vaccine for horses.
Now you can help protect your horse with LEPTO EQ INNOVATOR®, the first and only equine vaccine to help prevent leptospirosis. LEPTO EQ INNOVATOR helps prevent leptospiremia caused by L. pomona, which could, but has not be demonstrated to, help reduce the potential risk of equine recurrent uveitis (ERU) infections, abortions or acute renal failure caused by L. pomona.*
See if your horse is at risk by taking the Leptospirosis Risk Assessment.
Take Assessment
*Currently, there are no vaccines available with USDA-licensed label claims against equine abortions, uveitis or acute renal failure due to L. pomona.
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1 Data on file, Study Report No. Restricted Grant-FTLEPTO13 (v1.0) TI-01366, Zoetis LLC.
2 Divers TJ, Chang Y-F. Leptospirosis. In: Robinson NE, Sprayberry KA, eds. Current Therapy in Equine Medicine. Vol 6. 6th ed. St. Louis, MO: Saunders Elsevier;2009:145-147.
3 Thomas H. Leptospirosis in horses. Equine Chronicle. January/February 2015. http://www.equinechronicle.com/leptospirosis-in-horses. Accessed September 6, 2016.
4 Polle F, Storey E, Eades S, et al. Role of intraocular Leptospira infections in the pathogenesis of equine recurrent uveitis in the southern United States. J Equine Vet Sci.2014;34(11-12):1300-1306.
5 Borstel MV, Oey L, Strutzberg-Minder K, Boeve MH, Ohnesorge B. Direkter und indirekter Nachweis von Leptospiren aus Glasköperproben von Pferden mit ERU. Pferdeheilkunde. 2010;2(März/April):219-225.
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