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Excede Expectations

1 single shot.
2 critical stages of development.
7 full days of protection.

One injection of EXCEDE® for Swine (ceftiofur crystalline free acid) Sterile Suspension treats and controls swine respiratory disease for 7 days. It continuously attacks a broad range of pathogens.* And EXCEDE is proven effective for both weaning and nursery—the 2 critical stages in a young pig’s development. So you can have a healthy pig—and a healthy herd—for the long term.

*A pleuropneumoniae, H parasuis, P multocida, S suis.

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  • Count on EXCEDE
    Swine respiratory disease (SRD) continues to be an important health concern for producers. EXCEDE offers treatment against the following bacteria associated with SRD:

    • Actinobacillus pleuropneumoniae
    • Pasteurella multocida
    • Haemophilus parasuis
    • Streptococcus suis

    It also controls SRD associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, and Streptococcus suis in groups of pigs where SRD has been diagnosed.

    These bacteria are extremely sensitive to ceftiofur, as the chart below shows. The minimum inhibitory concentration (MIC) values for these pathogens are very low.

    MIC values from field trial isolates 

    Pathogen

    Number of Isolates

    MIC90*(µg/mL)

    A. pleuropneumoniae

    28

    ≤ 0.03

    P. multocida

    58

    ≤ 0.03

    S. suis type II

    41

    0.12

    H. parasuis**

    72

    0.06

    *MIC for 90 percent of the isolates.
    ** These MIC data were obtained during NCCLS procedures, but quality control values for
    H. parasuis had not been standardized.

    Seven days of treatment

    EXCEDE is the only single dose injectable antibiotic approved for swine that delivers at least 7 days of therapeutic plasma levels with one injection1. This makes it the right product to use first for treating SRD.

    The figure below shows the plasma profile for a single intramuscular injection (IM) dose of 5.0 mg/kg EXCEDE for Swine compared with three consecutive daily IM doses of 3.0 mg/kg of NAXCEL® (ceftiofur sodium) Sterile Powder.

    Plasma Concentrations of Active Metabolite

    EXCEDE offers the convenience and confidence you need in one dose.

    1. Study 1121R-60-04-215
  • EXCEDE is a prescription product. Administer by intramuscular injection (IM) in the post-auricular region of the neck as a single dosage of 2.27 mg ceftiofur equivalent (CE)/lb (5.0 mg CE/kg) body weight. This is equivalent to 1.0 mL per 44 lbs (20 kg) body weight (BW). No more than 2.0 mL should be injected in a single injection site.

    As with all drugs, EXCEDE® for Swine should not be administered to pigs known to be hypersensitive to cephalosporins or penicillins. Following label use as a single treatment, a 14-day pre-slaughter withdrawal period is required.

    Packaging

    • EXCEDE is available in 100 mL vials.

 

IMPORTANT SAFETY INFORMATION
People with known hypersensitivity to penicillin or cephalosporins should avoid exposure to EXCEDE. Do not use in swine found to be hypersensitive to the product. Pre-slaughter withdrawal time is 14 days following the last dose.

 

 Product and Prescribing Information