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RespiSure-ONE®

Help protect them from Day 1

RespiSure-ONE’s new label claims mean you can now vaccinate for mycoplasmal pneumonia when you process baby pigs. This is important because M. hyopneumoniae may infect pigs within the first three weeks of life.1, 2  When your goal is healthy herds, RespiSure-ONE is Early. Easy. Effective.

 

1. Fano E, Pijoan C, Dee S, Deen J. Effect of Mycoplasma hyopneumoniae colonization at weaning on disease severity in growing pigs. Can J Vet Res. 2007;71:195-200.

2. Sibila M, Nofrarias M, Lopez-Soria S, Segales J, Riera P, Llopart D, Calsamiglia M. Exploratory field study on Mycoplasma hyopneumoniae infection in suckling pigs. Vet Microbiol. 2007;121:352-356.

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  • Protection from the start

    Common in growing and finishing pigs, mycoplasmal pneumonia is a widespread, chronic disease characterized by coughing, stunted growth and reduced feed efficiency. RespiSure-ONE is the only vaccine labeled to aid in reducing chronic pneumonia, severity of colonization and shedding of Mycoplasma hyopneumoniae. And now, with RespiSure-ONE’s new label claims, you can help protect newborn pigs as soon as one day of age.

    Early
    Early vaccination is important. Pigs may be infected with M. hyopneumoniae during the first three weeks of life.1,2 Plus, early vaccination can help reduce potential clinical disease in the nursery.3

    Easy
    Now you have the convenience of vaccinating at processing. The most flexible label claim on the market lets you decide what’s best for your herd. One-dose administration saves time and labor.

    Effective
    When challenged, pigs vaccinated at one day showed reduced lung lesions, colonization and shedding.4 RespiSure-ONE is demonstrated safe for use in day-old pigs.4 Duration of immunity in 1-day-old pigs has not been established.

    • Reduction in severity of M. hyopneumoniae colonization. Pigs vaccinated at 1 day of age had an 85% reduction in the number of mycoplasma bacterial cells in bronchial swab samples when compared to non-vaccinated controls.4
    • Reduction of M. hyopneumoniae shedding. At 17, 21 and 24 days after challenge, the percentage of RespiSure-ONE vaccinates that shed M. hyopneumoniae was less than the control pigs.4
    • 25-week duration of immunity. Pigs vaccinated at 3 to 8 days of age and challenged 25 weeks later had a 95% reduction in lung lesions and a significantly superior serological response, compared to non-vaccinated controls.5
    • Improved immune response. Amphigen, the adjuvant in RespiSure-ONE, helps provide a duration of immunity with a high degree of safety, ease of use and syringeability.

    References:

    1. Fano E, Pijoan C, Dee S, Deen J. Effect of Mycoplasma hyopneumoniae colonization at weaning on disease severity in growing pigs. Can J Vet Res. 2007;71:195-200.
    2. Sibila M, Nofrarias M, Lopez-Soria S, Segales J, Riera P, Llopart D, Calsamiglia M. Exploratory field study on Mycoplasma hyopneumoniae infection in suckling pigs. Vet Microbiol. 2007;121:352-356.
    3. Connor JF. Early pig vaccination disease breakthrough. National Hog Farmer 2009;27.
    4. Data on file, Study Report No. 3127R-60-07-552, Pfizer Inc.
    5. Data on file, Study Report Nos. 3121C-60-99-227 and 3121C-60-99-223, Pfizer Inc.

  • General Directions
    Shake well. Aseptically administer a 2-mL dose intramuscularly.

    Primary Vaccination
    Aseptically administer a single 2-mL dose to healthy swine one day of age or older.

    Revaccination
    Administer a single 2-mL dose semiannually.

    Good animal husbandry and herd health management practices should be employed.

    Packaging
    50-, 250- and 500-dose vials.