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Proactive E. Coli Prevention

Poulvac® E. coli

Escherichia coli Vaccine, Live Culture

Stop disease before it stops you. Poulvac E. coli is the only commercially available modified-live vaccine designed for proactive prevention of disease caused by Avian Pathogenic E. coli (APEC). A broad-spectrum vaccine, Poulvac E. coli protects against infection early and decreases mortality to optimize bird performance and production. Proactive vaccination can help increase economic value by improving bird health and increasing overall performance.1,2

  • Helps reduce flock mortality
  • Simple application
  • Proactive prevention of diseases and symptoms related to E. coli
  • Demonstrated enhanced bird productivity and performance
  • Increased economic value
  • Multi-dose treatment options that greatly improve overall performance

E. coli causes millions of dollars in losses every year. Poulvac E. coli is well-suited to help prevent disease caused by E. coli that can significantly impact flock performance. Help your birds before they need it with Poulvac E. coli.

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  • Supplied in 10 x 5,000 and 25,000 dose units

    Spray Administration:

    1. Remove seal and stopper. Half fill vial with cool distilled water. Replace stopper and shake until dissolved.
    2. Pour rehydrated vaccine into a clean container and add cool distilled water to dilute the vaccine as indicated for your specific coarse spray vaccination machine or watering system.
    3. Administer at a rate of 1 dose of prepared vaccine per bird.

    Chickens: Vaccinate healthy chickens at 1 day-of-age or older by coarse spray or drinking water as an aid in the prevention of disease caused by Escherichia coli. A second vaccination is recommended for long-lived birds at 12 – 14 weeks of age.

    Turkeys: Vaccinate by coarse spray to healthy turkeys at 3 days-of-age as an aid in the prevention of disease caused by Escherichia coli. Follow with a second dose at 3 weeks-of-age.

    • For Veterinary use only. 
    • If possible, vaccinate all susceptible birds on the premises at the same time.
    • For 10 to 14 days after vaccinating, avoid carrying vaccine particles on shoes, clothing, etc. into areas where there are nonvaccinated birds.
    • Concurrent use of antibiotics with this vaccine is not recommended.
    • Federal regulations prohibit the repackaging or sale of the contents of the 10 x 5,000 dose carton in fractional units. Do not accept if seal is broken.

    Storage and Handling:

    • Store in the dark at 35° – 45°F (2° – 7°C).
    • Use entire contents when first opened.
    • Burn containers and all unused contents.
    1. Data on file, Study Report Nos. PPH-0001, PPH-0003 and PPH-0004, Zoetis Inc.
    2. Data on file, Study Report No. PPH-006, Zoetis Inc.


Important Safety Information

  • Not for human use.
  • Do not vaccinate within 21 days before slaughter.