Print page content Print
Increase text size Decrease text size
Text Size

Dosing and administration


Poulvac® E. coli is recommended as an aid in the prevention of disease caused by E. coli. Presentation:

  • 10 x 5,000 doses
  • 1 x 20,000 doses

Composition: Live E. coli bacterium
Formulation: Live culture
Withholding period: 21 days before slaughter

Vaccination programs

Chickens: Vaccinate healthy chickens at 1 day of age or older by coarse spray or drinking water as an aid in the prevention of disease caused by E. coli. A second vaccination is recommended for long-lived birds at 12 to 14 weeks of age.

Turkeys: Vaccinate by coarse spray to healthy turkeys at 3 days of age as an aid in the prevention of disease caused by E. coli. Follow with a second dose at 3 weeks of age.

Directions for spray administration

  1. Remove seal and stopper. Half-fill vial with cool distilled water. Replace stopper and shake until dissolved.
  2. Pour rehydrated vaccine into a clean container and add cool distilled water to dilute the vaccine as indicated for your specific coarse spray vaccination machine or watering system.
  3. Administer at a rate of 1 dose of prepared vaccine per bird.


For veterinary use only.

  • If possible, vaccinate all susceptible birds on the premises at the same time.
  • For 10 to 14 days after vaccinating, avoid carrying vaccine particles on shoes, clothing, etc. into areas where there are non-vaccinated birds.
  • Concurrent use of antibiotics with this vaccine is not recommended.

Storage and handling

  • Store in the dark at 35° to 45°F (2° to 7°C).
  • Use entire contents when first opened.
  • Burn containers and all unused contents.

Program Protection Levels



We are Mon–Fri, 8am–8pm ET

email to

This site is intended for U.S. Animal Healthcare Professionals.

All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. ©2019 Zoetis Services LLC. All rights reserved.